BDB561337

IL-17F Mouse anti-Human, V450, Clone: O33-782, BD

Manufacturer: Fischer Scientific

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Antigen

IL-17F

Classification

Monoclonal

Conjugate

Violet Fluor 450 (V450)

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen

Human IL-17F

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

O33-782

Description

Interleukin-17F; cytokine ML-1; ML-1; IL-24

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The O33-782 monoclonal antibody specifically binds to Interleukin-17F (IL-17F)
  • IL-17F is a member of the IL-17 family of cytokines
  • IL-17F is encoded by the IL17F gene located in chromosome 6 (location: 6p12)
  • IL-17F is a proinflammatory cytokine that is produced by activated T cells including differentiated CD4+ T helper 17 (Th17) cells
  • Activated Th17 cells can express disulfide-linked IL-17F and IL-17A homodimers as well as IL-17A/IL-17F heterodimers
  • These IL-17 dimers act by binding to and signaling through IL-17 receptor complexes (IL-17R)
  • IL-17R are comprised of transmembrane IL-17RA and IL-17-RC protein subunits that are expressed by a variety of target cells including epithelial and endothelial cells, keratinocytes, fibroblasts, and granulocytes
  • IL-17F can induce target cells to produce proinflammatory cytokines such as IL-1β, IL-6, G-CSF, GM-CSF, and TNF and chemokines including CXCL1/Gro-α, CXCL2/Gro-β, and CXCL8/IL-8 that attract and activate leukocytes, eg, neutrophils
  • Th17 and other IL-17F-producing cells play protective roles in the clearance of extracellular pathogens, including bacteria and fungi
  • IL-17F can also play adverse roles in inflammation associated with asthma and autoimmune diseases
  • Host Species: Mouse Clone: SCPL1362 Isotype: IgG1 κ Species Reactivity: Human

Compare Similar Items

Show Difference

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Fischer Scientific

BDB561337

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Antigen:
IL-17F

Classification:
Monoclonal

Conjugate:
Violet Fluor 450 (V450)

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Human IL-17F

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
O33-782

Description:
Interleukin-17F; cytokine ML-1; ML-1; IL-24

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

Fischer Scientific

BDB561338

--


Antigen:
IL-17F

Classification:
Monoclonal

Conjugate:
Violet Fluor 450 (V450)

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Human IL-17F

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
O33-782

Description:
Interleukin-17F; cytokine ML-1; ML-1; IL-24

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB561339

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Antigen:
HLA-A2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
BB7.2

Description:
HLA class I histocompatibility antigen A2 alpha chain

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

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BDB561340

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Antigen:
CD107a

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Human Adult Adherent Peripheral Blood Cells

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
H4A3

Description:
LAMP1; LAMP-1; LAMPA; LGP120

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ