BDB561444

CD39 Mouse anti-Human, FITC, Clone: TU66 (also known as Tü 66, Tü66), BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB561444-Each-of-1 In Stock ₹ 24,769.62

BDB561444 - Each of 1

₹ 24,769.62

In Stock

Quantity

1

Base Price: ₹ 24,769.62

GST (18%): ₹ 4,458.532

Total Price: ₹ 29,228.152

Antigen

CD39

Classification

Monoclonal

Conjugate

FITC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

TU66 (also known as Tü 66, Tü66)

Description

ENTPD1; NTPDase-1; Ecto-ATPase 1; Ecto-ATPDase 1

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The TU66 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) an ectoenzyme that degrades ATP to AMP
  • It is a member of the family of ectonucleoside triphosphate dihydrolases (E-NTPDases) known to be involved in regulation of extracellular nucleotide catabolism, controlling the extracellular nucleoside triphosphate pool (NTP)
  • CD39 is expressed on a subset of T cells, B cells and dendritic cells with weak staining of monocytes and granulocytes
  • Recently, CD39 has been found to be expressed primarly by immune-suppressive Foxp3(+) regulatory T (Treg) cells in both human and mice
  • In humans, CD39 is restricted to a subset of Foxp3+ regulatory effector/memory-like T cells
  • In mice, the enzyme is present on most if not all CD4+CD25+ cells and CD39 expression is driven by Foxp3
  • It is thought that CD39 allows Treg cells to enter inflamed areas where high levels of ATP are present.

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Antigen:
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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
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Human

Isotype:
IgG2b κ

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Flow Cytometry

Clone:
TU66 (also known as Tü 66, Tü66)

Description:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

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