BDB561525

Bcl-6 Mouse, Alexa Fluor 647, Clone: K112-91, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB561525-Each-of-1 In Stock ₹ 25,154.64

BDB561525 - Each of 1

₹ 25,154.64

In Stock

Quantity

1

Base Price: ₹ 25,154.64

GST (18%): ₹ 4,527.835

Total Price: ₹ 29,682.475

Antigen

Bcl-6

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Bcl-6 Recombinant Protein

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

K112-91

Description

BCL6; B-cell lymphoma 6 protein; LAZ3; Laz-3, ZBTB27, ZNF51

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG1 κ

Description

  • The K112-91 monoclonal antibody specifically binds to Bcl-6
  • Bcl-6 was first identified as a proto-oncogene frequently deregulated by chromosomal translocations in non-Hodgkin B-cell lymphomas
  • It is a nuclear transcriptional repressor of the BTB/POZ zinc-finger family of transcription factors
  • In addition to its roles in cancer, Bcl-6 plays important roles in the differentiation of normal cells including B cells, thymocytes, CD4+ or CD8+ T cells
  • Bcl-6 is highly expressed in germinal center B cells, where it promotes the germinal center reaction by inducing proliferation and inhibiting the DNA-damage response
  • Bcl-6 has been identified as a key factor in promoting the differentiation of CD4+ follicular T helper (Tfh) cells that are involved in promoting germinal center formation and providing help to B cells
  • The interplay of Bcl-6 and another transcriptional repressor, Blimp-1, is thought to be critical in defining the results of both B-cell and T-cell differentiation.

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BD Biosciences

BDB561525

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Antigen:
Bcl-6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Bcl-6 Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
K112-91

Description:
BCL6; B-cell lymphoma 6 protein; LAZ3; Laz-3, ZBTB27, ZNF51

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

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BDB561529

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Antigen:
T- and B-Cell Activation Antigen

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
In vitro-activated T-cell-depleted CBA/Ca mouse splenocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
GL7

Description:
GL7

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgM κ

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BD Biosciences

BDB561530

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Antigen:
T- and B-Cell Activation Antigen

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
In vitro-activated T-cell-depleted CBA/Ca mouse splenocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
GL7

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgM κ

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Antigen:
CD36

Classification:
Monoclonal

Conjugate:
Violet Fluor 450 (V450)

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Human Platelet Extracts

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
CB38 (also known as NL07)

Description:
GPIIIb; Platelet GPIV; OKM5-antigen; PASIV

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ