BDB561656

IL-17F Mouse anti-Mouse, PE, Clone: O79-289, BD

Manufacturer: Fischer Scientific

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Antigen

IL-17F

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Il17f; interleukin 17F; Interleukin-17F

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

O79-289

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse IL-17F Recombinant Protein

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The O79-289 monoclonal antibody specifically binds to the inflammatory cytokine protein, Interleukin-17 (IL-17F)
  • IL-17F is a member of the IL-17 family of cytokines
  • Among IL-17 family members, IL-17F has the highest amino acid sequence homology to IL-17A
  • IL-17F is produced by activated CD4+ T helper (Th17) cells, CD8+ T (Tc17) cells and γδ T cells
  • IL-17F can be secreted as homodimers or as heterodimers with IL-17A
  • IL-17F and IL-17A have overlapping functions such as inducing epithelial cells and fibroblasts to produce proinflammatory cytokines and chemokines including IL-6, GM-CSF, CXCL1, CCL2, and CCL7
  • These factors attract and activate neutrophils and other cell types that mediate protective responses against pathogenic microbes or pathologic allergic or autoimmune diseases
  • IL-17 gene knockout studies have shown that IL-17F and IL-17A have independent functions as well
  • IL-17F and IL-17A exert their biological function by binding to and signaling through IL-17 receptors comprised of the transmembrane receptor subunits, IL-17RA (CD217) and IL-17RC.

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Fischer Scientific

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Antigen:
IL-17F

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Il17f; interleukin 17F; Interleukin-17F

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
O79-289

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse IL-17F Recombinant Protein

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD294

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
BM16

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Quantity:
50 μg

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
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Concentration:
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Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
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Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
BM16

Conjugate:
PerCP-Cyanine5.5

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human CRTH2 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
Pax-6

Classification:
Monoclonal

Concentration:
__

Description:
Oculorhombin, Aniridia type II protein, PAX6, AN2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
O18-1330

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
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Quantity:
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.