BDB561719

CD154 Hamster anti-Mouse, PE, Clone: MR1, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561719-Each-of-1 In Stock ₹ 8,556.00

BDB561719 - Each of 1

₹ 8,556.00

In Stock

Quantity

1

Base Price: ₹ 8,556.00

GST (18%): ₹ 1,540.08

Total Price: ₹ 10,096.08

Antigen

CD154

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CD40 Ligand, gp39

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG3 κ

Applications

Flow Cytometry

Clone

MR1

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Activated mouse Th1 clone D1.6

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The MR1 antibody reacts with CD154 (CD40 Ligand, gp39), an accessory molecule expressed on activated T helper (CD4+) lymphocytes
  • CD154 has also been detected on other types of leukocytes, including CD8+ T cells, medullary thymocytes, activated CD4+ NK-T cells, and human NK cells
  • CD154 plays an important role in costimulatory interactions between T and B lymphocytes and between antigen-presenting cells and lymphocytes, regulating the immune response at multiple levels
  • MR1 mAb inhibits in vitro activation of B lymphocytes by T helper cells by blocking interaction of gp39 with CD40
  • In vitro interactions of T cells and antigen-presenting cells can also be blocked by the MR1 antibody
  • In vivo treatment with MR1 antibody blocks the development of experimental autoimmune disease, inhibits formation of germinal centers and generation of memory B cells, reduces T-lymphocyte responses to allogeneic cells and allografts, prevents intrathymic deletion of self-reactive T lymphocytes, and disrupts antigen-specific T-cell responses.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB561719

--


Antigen:
CD154

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CD40 Ligand, gp39

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG3 κ

Applications:
Flow Cytometry

Clone:
MR1

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Activated mouse Th1 clone D1.6

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB561720

--


Antigen:
CD154

Classification:
Monoclonal

Concentration:
__

Description:
CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
TRAP1

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB561721

--


Antigen:
CD154

Classification:
Monoclonal

Concentration:
__

Description:
CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
TRAP1 (also known as TRAP-1)

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB561722

--


Antigen:
CD154

Classification:
Monoclonal

Concentration:
__

Description:
CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
TRAP1 (also known as TRAP-1)

Conjugate:
PE-Cyanine5

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.