BDB561750
CD195 Mouse anti-Human, PE-Cy5, Clone: 2D7/CCR5, BD
Manufacturer: Fischer Scientific
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Antigen
CD195
Classification
Monoclonal
Conjugate
PE-Cyanine5
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Human CCR5 Transfected Cell Line
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
2D7/CCR5
Description
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Description
- The 2D7/CCR5 monoclonal antibody specifically binds to the human chemokine receptor, CCR5
- CCR5 is also known as CD195
- CCR5 is a seven transmembrane-spanning G protein-associated molecule
- CCR5 belongs to the beta chemokine receptor family
- It is expressed on a subset of T lymphocytes (CD3+CD45RO+CD95+)
- CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation
- It signals a response to at least three chemokines: Regulated upon Activation Normal T-cell Expressed and Secreted (RANTES), Macrophage Inflammatory Protein-1 (MIP-1) and Monocyte Chemoattractant Protein 2 (MCP-2)
- Additionally, CCR5 has been found to be a coreceptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission
- Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele, demonstrate resistance to HIV infection
- This antibody has been shown to block ligand and gp120 binding
- It is also able to neutralize HIV infection.
Compare Similar Items
Show Difference
Antigen: CD195
Classification: Monoclonal
Conjugate: PE-Cyanine5
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Human CCR5 Transfected Cell Line
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 2D7/CCR5
Description: CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD195
Classification:
Monoclonal
Conjugate:
PE-Cyanine5
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Human CCR5 Transfected Cell Line
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
2D7/CCR5
Description:
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD196
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human CD196/CCR6 Peptide
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 11A9
Description: BN-1; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; CD196
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD196
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human CD196/CCR6 Peptide
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
11A9
Description:
BN-1; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; CD196
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD196
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse CCR6-transfected Rat Cell Line
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 140706
Description: CCR6, BN-1, CKR-L3, DRY6, KY411, GPR-CY4, STRL22
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a
Antigen:
CD196
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse CCR6-transfected Rat Cell Line
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
140706
Description:
CCR6, BN-1, CKR-L3, DRY6, KY411, GPR-CY4, STRL22
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a
Antigen: CD1a
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: __
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: HI149
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD1a
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
HI149
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ