BDB561773
CD23 Rat anti-Mouse, PE, Clone: B3B4, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561773-Each-of-1 | In Stock | ₹ 7,187.04 |
BDB561773 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 7,187.04
GST (18%): ₹ 1,293.667
Total Price: ₹ 8,480.707
Antigen
CD23
Classification
Monoclonal
Concentration
0.2mg/mL
Description
FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
B3B4
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The B3B4 antibody reacts with CD23, the low affinity IgE Fc receptor (FcεRII) expressed on mature resting conventional B lymphocytes, but not on B-1 cells (CD5+ B cells) or T lymphocytes
- It does not react with high-affinity IgE receptors, as demonstrated on mouse mast cell lines
- The regulation of CD23 surface expression on activated B cells appears to be complex, depending upon the mode of activation and the presence of cytokines
- IgE synthesis is negatively regulated by CD23, and CD23 expression is upregulated on splenocytes in the presence of IgE
- CD23 is also upregulated on follicular dendritic cells in the lymph nodes of immunized mice, and a subset of splenic dendritic cells expresses CD23
- The B3B4 antibody abrogates antigen-specific IgE-dependent modulation of immune responses in normal mice
- This monoclonal antibody also blocks IgE binding and eosinophil infiltration in the lung of immunized mice
- Different in vivo results have been obtained when using the intact B3B4 antibody or the F(ab')2 fragments
- B3B4 mAb does not cross-react with rat or human IgE Fc Receptor.
Compare Similar Items
Show Difference
Antigen: CD23
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: B3B4
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD23
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
B3B4
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD235a
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Glycophorin-A; GYPA; GPA; PAS-2; MN sialoglycoprotein; Sialoglycoprotein A
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: GA-R2 (HIR2)
Conjugate: APC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD235a
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Glycophorin-A; GYPA; GPA; PAS-2; MN sialoglycoprotein; Sialoglycoprotein A
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
GA-R2 (HIR2)
Conjugate:
APC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD235a
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Glycophorin-A; GYPA; GPA; PAS-2; MN sialoglycoprotein; Sialoglycoprotein A
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: GA-R2 (HIR2)
Conjugate: PE-Cyanine5
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: __
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD235a
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Glycophorin-A; GYPA; GPA; PAS-2; MN sialoglycoprotein; Sialoglycoprotein A
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
GA-R2 (HIR2)
Conjugate:
PE-Cyanine5
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD24
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: CD24a; HSA; Heat Stable Antigen; Ly-52; Nectadrin; R13-Ag
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: M1/69
Conjugate: FITC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: C57BL/10 Mouse Splenic T Lymphocytes
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD24
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
CD24a; HSA; Heat Stable Antigen; Ly-52; Nectadrin; R13-Ag
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
M1/69
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
C57BL/10 Mouse Splenic T Lymphocytes
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.