BDB561788
CD279 Hamster anti-Mouse, PE, Clone: J43, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561788-Each-of-1 | In Stock | ₹ 8,898.24 |
BDB561788 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 8,898.24
GST (18%): ₹ 1,601.683
Total Price: ₹ 10,499.923
Antigen
CD279
Classification
Monoclonal
Concentration
0.2mg/mL
Description
PD-1
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2 κ
Applications
Flow Cytometry
Clone
J43
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- Description The J43 antibody reacts with CD279 (PD-1), a 50-55-kDa glycoprotein encoded by the Pdcd1 gene of the CD28 family of the Ig superfamily
- The expression of Pdcd1 mRNA and PD-1 protein is tightly regulated
- PD-1 is transiently expressed on CD4-CD8thymocytes, it is upregulated on some cell lines upon induction of apoptosis, it is induced on thymocytes and splenic T and B lymphocytes after stimulation through their antigen receptors, and it is induced on activated myeloid cells
- In addition, Pdcd1 mRNA is transiently expressed in developing B lymphocytes at the pro-B-cell stage
- The presence of an ITIM ( I mmunoreceptor nhibitory M otif) on PD-1's intracytoplasmic region and the development of splenomegaly and breakdown of peripheral tolerance in PD-1[-/-] mice suggest that PD-1 may be involved in the negative regulation of immune responses
- The PD-1 ligands, B7-H1 (also known as PD-L1) and B7-DC (PD-L2), are members of the B7 family of the Ig superfamily
- The J43 antibody blocks the binding of PD-1 to its two ligands.
Compare Similar Items
Show Difference
Antigen: CD279
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: PD-1
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2 κ
Applications: Flow Cytometry
Clone: J43
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD279
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
PD-1
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2 κ
Applications:
Flow Cytometry
Clone:
J43
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD28
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2 λ1
Applications: Flow Cytometry
Clone: 37.51
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse EL-4 (T-cell lymphoma) Cells
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD28
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2 λ1
Applications:
Flow Cytometry
Clone:
37.51
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse EL-4 (T-cell lymphoma) Cells
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD28
Classification: Monoclonal
Concentration: __
Description: CD28 antigen; T44; Tp44; TP44
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: CD28.2
Conjugate: FITC
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human CD28 Transfected Cell Line
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD28
Classification:
Monoclonal
Concentration:
__
Description:
CD28 antigen; T44; Tp44; TP44
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
CD28.2
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human CD28 Transfected Cell Line
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD28
Classification: Monoclonal
Concentration: __
Description: CD28 antigen; T44; Tp44; TP44
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: CD28.2
Conjugate: APC
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human CD28 Transfected Cell Line
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD28
Classification:
Monoclonal
Concentration:
__
Description:
CD28 antigen; T44; Tp44; TP44
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
CD28.2
Conjugate:
APC
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human CD28 Transfected Cell Line
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.