BDB561987
Cutaneous Lymphocyte Antigen Rat anti-Human, FITC, Clone: HECA-452, BD
Manufacturer: Fischer Scientific
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Antigen
Cutaneous Lymphocyte Antigen
Classification
Monoclonal
Conjugate
FITC
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Lymphocyte-depleted Stromal Preparation of Tonsil
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
HECA-452
Description
CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human, Mouse
Isotype
IgM κ
Description
- The HECA-452 monoclonal antibody specifically reacts with Cutaneous Lymphocyte Associated Antigen (CLA), a carbohydrate domain shared by sialyl Lewis[x] (sLe[x]) and sialyl Lewis[a] (sLe[a]) antigens
- It serves as a ligand for selectins including CD62E (E-selectin; ELAM-1)
- CLA is expressed on high endothelium and on lymphocytes including most T lymphocytes infiltrating cutaneous sites of inflammation
- Amongst peripheral blood cells, it is expressed on monocytes and granulocytes and a subset of lymphocytes
- The HECA-452 antibody is also reportedly crossreactive with the mouse CLA carbohydrate epitope that is transiently expressed by PSGL-1/CD162 on activated T cells
- A number of studies suggest that CLA plays an important role in supporting leucocyte adhesive interactions and migration into extravascular tissues during inflammation
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Compare Similar Items
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Antigen: Cutaneous Lymphocyte Antigen
Classification: Monoclonal
Conjugate: FITC
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Lymphocyte-depleted Stromal Preparation of Tonsil
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: HECA-452
Description: CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Isotype: IgM κ
Antigen:
Cutaneous Lymphocyte Antigen
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Lymphocyte-depleted Stromal Preparation of Tonsil
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
HECA-452
Description:
CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Isotype:
IgM κ
Antigen: CXCR5
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse CXCR5
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 2G8
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CXCR5
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse CXCR5
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
2G8
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: TCR γδ
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: B1
Description: TCRgd; γδ TCR; TRG@, TRD@; TCRG, TCRD; TCR gamma delta
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
TCR γδ
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
B1
Description:
TCRgd; γδ TCR; TRG@, TRD@; TCRG, TCRD; TCR gamma delta
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: TCR gammaδ
Classification: Monoclonal
Conjugate: FITC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
Quantity: 0.05 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: GL3
Description: __
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2 κ
Antigen:
TCR gammaδ
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
Quantity:
0.05 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
GL3
Description:
__
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2 κ