BDB562164
NKG2D Mouse anti-Human, NA/LE, Unlabeled, Clone: 1D11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562164-Each-of-1 | In Stock | ₹ 45,517.92 |
BDB562164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,517.92
GST (18%): ₹ 8,193.226
Total Price: ₹ 53,711.146
Antigen
NKG2D
Classification
Monoclonal
Concentration
1.0mg/mL
Description
CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
1D11
Conjugate
Unconjugated
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
NKL cells
Quantity
0.5 mg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Related Products
Description
- The 1D11 monoclonal antibody specifically binds to NKG2D, a 42 kDa type II transmembrane glycoprotein that is also known as CD314 and KLRK1
- NKG2D is a member of the C-type lectin family and is expressed on human NK cells
- This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types
- Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells
- It is also expressed on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
- NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells
- Importantly, NKG2D can complement the role of NCR in tumor cell lysis
- Remarkably, the combined maskings of NCR and NKG2D can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
- The 1D11 antibody can reportedly block or stimulate the function of NKG2D-positive cells.
Compare Similar Items
Show Difference
Antigen: NKG2D
Classification: Monoclonal
Concentration: 1.0mg/mL
Description: CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 1D11
Conjugate: Unconjugated
Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen: NKL cells
Quantity: 0.5 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
NKG2D
Classification:
Monoclonal
Concentration:
1.0mg/mL
Description:
CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
1D11
Conjugate:
Unconjugated
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen:
NKL cells
Quantity:
0.5 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: CD45
Classification: Monoclonal
Concentration: 1.0mg/mL
Description: Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 30-F11
Conjugate: Unconjugated
Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen: Mouse Thymus / Spleen
Quantity: 0.5 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
CD45
Classification:
Monoclonal
Concentration:
1.0mg/mL
Description:
Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
30-F11
Conjugate:
Unconjugated
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen:
Mouse Thymus / Spleen
Quantity:
0.5 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: KLH
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: __
Isotype: IgG2
Applications: __
Clone: B81-3
Conjugate: Alexa Fluor 488
Formulation: __
Immunogen: Keyhole Limpet Hemocyanin
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: __
Antigen:
KLH
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
__
Isotype:
IgG2
Applications:
__
Clone:
B81-3
Conjugate:
Alexa Fluor 488
Formulation:
__
Immunogen:
Keyhole Limpet Hemocyanin
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
__
Antigen: CD140a
Classification: Monoclonal
Concentration: 1.0mg/mL
Description: Pdgfra; Pdgfr2; PDGF-R alpha; Platelet derived growth factor receptor alpha
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: APA5
Conjugate: Unconjugated
Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen: Mouse PDGF Receptor ? chain
Quantity: 0.5 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
CD140a
Classification:
Monoclonal
Concentration:
1.0mg/mL
Description:
Pdgfra; Pdgfr2; PDGF-R alpha; Platelet derived growth factor receptor alpha
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
APA5
Conjugate:
Unconjugated
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen:
Mouse PDGF Receptor ? chain
Quantity:
0.5 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C