BDB562401

Bcl-6 Mouse, PE-CF594, Clone: K112-91, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562401-Each-of-1 In Stock ₹ 25,282.98

BDB562401 - Each of 1

₹ 25,282.98

In Stock

Quantity

1

Base Price: ₹ 25,282.98

GST (18%): ₹ 4,550.936

Total Price: ₹ 29,833.916

Antigen

Bcl-6

Classification

Monoclonal

Conjugate

PE-CF594

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Bcl-6 Recombinant Protein

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

K112-91

Description

BCL6; B-cell lymphoma 6 protein; LAZ3; Laz-3, ZBTB27, ZNF51

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG1 κ

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Description

  • The K112-91 monoclonal antibody specifically binds to Bcl-6
  • Bcl-6 was first identified as a proto-oncogene frequently deregulated by chromosomal translocations in non-Hodgkin B-cell lymphomas
  • It is a nuclear transcriptional repressor of the BTB/POZ zinc-finger family of transcription factors
  • In addition to its roles in cancer, Bcl-6 plays important roles in the differentiation of normal cells including B cells, thymocytes, CD4+ or CD8+ T cells
  • Bcl-6 is highly expressed in germinal center B cells, where it promotes the germinal center reaction by inducing proliferation and inhibiting the DNA-damage response
  • Bcl-6 has been identified as a key factor in promoting the differentiation of CD4+ follicular T helper (Tfh) cells that are involved in promoting germinal center formation and providing help to B cells
  • The interplay of Bcl-6 and another transcriptional repressor, Blimp-1, is thought to be critical in defining the results of both B-cell and T-cell differentiation
  • This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
  • PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
  • Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).

Compare Similar Items

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BD Biosciences

BDB562401

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Antigen:
Bcl-6

Classification:
Monoclonal

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Bcl-6 Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
K112-91

Description:
BCL6; B-cell lymphoma 6 protein; LAZ3; Laz-3, ZBTB27, ZNF51

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

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BD Biosciences

BDB562403

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Antigen:
CD25

Classification:
Monoclonal

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
M-A251

Description:
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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BD Biosciences

BDB562405

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Antigen:
CD24

Classification:
Monoclonal

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
ML5

Description:
Heat Stable Antigen Homologue (HSA); Ba-1; CD24A

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

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BDB562406

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Antigen:
CD3

Classification:
Monoclonal

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Purified Human CD3ε Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
SP34-2

Description:
CD3E; CD3-epsilon; T3E; TCRE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Rhesus Monkey

Isotype:
IgG1 λ