BDB562421
FoxP3 Mouse anti-Human, PE-CF594, Clone: 259D/C7, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562421-Each-of-1 | In Stock | ₹ 25,967.46 |
BDB562421 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,967.46
GST (18%): ₹ 4,674.143
Total Price: ₹ 30,641.603
Antigen
FoxP3
Classification
Monoclonal
Conjugate
PE-CF594
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
FoxP3 recombinant protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
259D/C7
Description
Forkhead box P3; IPEX; JM2; PIDX: Scurfin; XPID
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Related Products
Description
- The 259D/C7 antibody monoclonal antibody specifically binds to the human FoxP3 transcription factor, a member of the forkhead or winged helix family of transcription factors
- The expression of FoxP3, also known as Scurfin, IPEX and JM2, has been found to be associated with CD4+ regulatory T cells and represents a specific marker for these cells
- Flow cytometric analysis has shown that FoxP3 is expressed by the majority of CD4+CD25+high T cells in peripheral blood while less than half of CD4+CD25int cell population are FoxP3 positive
- Approximately 5-10% of peripheral CD4+ cells are CD4+CD25+ T regulatory cells
- T regulatory cells are thought to play a critical role in the control of T cell mediated autoimmunity by suppressing the proliferation and cytokine production of other T cells
- To support this hypothesis, it has been found that FOXP3 is mutated in scurfy (sf) mice
- The 259D/C7 antibody reacts with all currently identified isoforms of human FoxP3 and is cross-reactive with Cynomolgus, Rhesus and Baboon
- This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
- PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
- Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20nm filter)
- Host Species: Mouse Clone: 259D/C7 Isotype: IgG1 Species Reactivity: Human Immunogen: FoxP3 recombinant protein Intracellular Staining
Compare Similar Items
Show Difference
Antigen: FoxP3
Classification: Monoclonal
Conjugate: PE-CF594
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: FoxP3 recombinant protein
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 259D/C7
Description: Forkhead box P3; IPEX; JM2; PIDX: Scurfin; XPID
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
FoxP3
Classification:
Monoclonal
Conjugate:
PE-CF594
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
FoxP3 recombinant protein
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
259D/C7
Description:
Forkhead box P3; IPEX; JM2; PIDX: Scurfin; XPID
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Antigen: TGF-Beta1
Classification: Monoclonal
Conjugate: PE-CF594
Formulation: __
Immunogen: Human TGF-β1 Transfected Cell Line
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: __
Applications: __
Clone: TW4-9E7
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
TGF-Beta1
Classification:
Monoclonal
Conjugate:
PE-CF594
Formulation:
__
Immunogen:
Human TGF-β1 Transfected Cell Line
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
__
Applications:
__
Clone:
TW4-9E7
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Antigen: CD3
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: UCHT1
Description: CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD3
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
UCHT1
Description:
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD3
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: UCHT1
Description: CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD3
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
UCHT1
Description:
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ