BDB562472

MAPKAPK-2 Mouse, Alexa Fluor 647, Clone: P24-694, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562472-Each-of-1 In Stock ₹ 32,170.56

BDB562472 - Each of 1

₹ 32,170.56

In Stock

Quantity

1

Base Price: ₹ 32,170.56

GST (18%): ₹ 5,790.701

Total Price: ₹ 37,961.261

Antigen

MAPKAPK-2

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Phosphorylated human MAPKAPK-2 peptide

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

P24-694

Description

MAP kinase-activated protein kinase 2, MAPKAP kinase 2; MK2; MAPK2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG1 κ

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Description

  • Description The P24-694 monoclonal antibody specifically binds to the phosphorylated T334 site (pT334) of MAPKAPK-2
  • MAPKAPK-2 is a serine/threonine protein kinase
  • This ∽49 kDa member of the MAPKAPK family of protein kinases is also known as mitogen-activated protein kinase-activated protein kinase 2
  • MAPKAPK-2 is phosphorylated and activated by p38 MAP kinase in response to stress, cytokines and chemokines
  • MAPKAPK-2 is phosphorylated on multiple sites including Thr222, Ser272 and Thr334
  • Phosphorylation of any two of these three amino acid residues seems to be required for the activation of this kinase thatserves multiple cellular functions
  • Phosphorylation of Thr334 was reported to be essential for nuclear export of the heterodimer formed between p38 MAPK and MAPKAPK-2
  • Mice deficient in MAPKAPK-2 have been shown to be protected from ischemic injury
  • MAPKAPK-2 is also reported to serve as a cell cycle checkpoint kinase in response to UV irradiation
  • The heat shock protein, HSP27 was shown to be one of the major substrates of MAPK and MAPKAPK-2.

Compare Similar Items

Show Difference

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BD Biosciences

BDB562472

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Antigen:
MAPKAPK-2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated human MAPKAPK-2 peptide

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
P24-694

Description:
MAP kinase-activated protein kinase 2, MAPKAP kinase 2; MK2; MAPK2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Img

Fischer Scientific

BDB562475

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Antigen:
CD49f

Classification:
Monoclonal

Conjugate:
PerCP-Cyanine5.5

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Mouse mammary tumor cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
GoH3

Description:
ITGA6; IThe GoH3 monoclonal ntegrin alpha-6; Integrin α6 chain; VLA-6; ITA6

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

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BD Biosciences

BDB562476

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Antigen:
Ig κ chain C region

Classification:
Monoclonal

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
IgG2b ? secreted by MPC-11 plasmacytoma

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
187.1

Description:
Ig kappa chain C region; IGKC; Igk-C; Ig, κ

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

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BDB562478

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Antigen:
EZH2

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human EZH2 recombinant protein aa. 156-256

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
11/EZH2

Description:
Enhancer of zeste 2; ENX-1; Histone-lysine N-methyltransferase EZH2; KMT6

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1