BDB562825
CD23 Rat anti-Mouse, PE-Cy7, Clone: B3B4, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562825-Each-of-1 | In Stock | ₹ 23,272.32 |
BDB562825 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,272.32
GST (18%): ₹ 4,189.018
Total Price: ₹ 27,461.338
Antigen
CD23
Classification
Monoclonal
Concentration
0.2mg/mL
Description
FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Immunogen
FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity
0.1 mg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
B3B4
Conjugate
PE-Cyanine7
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The B3B4 antibody reacts with CD23, the low affinity IgE Fc receptor (FcεRII) expressed on mature resting conventional B lymphocytes, but not on B-1 cells (CD5+ B cells) or T lymphocytes
- It does not react with high-affinity IgE receptors, as demonstrated on mouse mast cell lines
- The regulation of CD23 surface expression on activated B cells appears to be complex, depending upon the mode of activation and the presence of cytokines
- IgE synthesis is negatively regulated by CD23, and CD23 expression is upregulated on splenocytes in the presence of IgE
- CD23 is also upregulated on follicular dendritic cells in the lymph nodes of immunized mice, and a subset of splenic dendritic cells expresses CD23
- The B3B4 antibody abrogates antigen-specific IgE-dependent modulation of immune responses in normal mice
- This monoclonal antibody also blocks IgE binding and eosinophil infiltration in the lung of immunized mice
- Different in vivo results have been obtained when using the intact B3B4 antibody or the F(ab')2 fragments
- B3B4 mAb does not cross-react with rat or human IgE Fc Receptor.
Compare Similar Items
Show Difference
Antigen: CD23
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Immunogen: FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: B3B4
Conjugate: PE-Cyanine7
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD23
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Immunogen:
FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
B3B4
Conjugate:
PE-Cyanine7
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: CD23
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Immunogen: FcΕR isolated from the mouse B hybridoma line O1.2B2
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: __
Applications: __
Clone: B3B4
Conjugate: Alexa Fluor 647
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a
Antigen:
CD23
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Immunogen:
FcΕR isolated from the mouse B hybridoma line O1.2B2
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
__
Applications:
__
Clone:
B3B4
Conjugate:
Alexa Fluor 647
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a
Antigen: CD18
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Integrin β2 chain; Itgb2; Integrin beta 2; LFA-1/CR3/p150,95 subunit beta
Immunogen: Cell membrane glycoproteins from mouse T-cell lymphoma BW5147
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: C71/16
Conjugate: PerCP-Cyanine5.5
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD18
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Integrin β2 chain; Itgb2; Integrin beta 2; LFA-1/CR3/p150,95 subunit beta
Immunogen:
Cell membrane glycoproteins from mouse T-cell lymphoma BW5147
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
C71/16
Conjugate:
PerCP-Cyanine5.5
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: H-2KB
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: H2 class I histocompatibility alloantigen Kb
Immunogen: Mouse C57BL splenocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: AF6-88.5
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
H-2KB
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
H2 class I histocompatibility alloantigen Kb
Immunogen:
Mouse C57BL splenocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
AF6-88.5
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ