BDB563523

CD61 Hamster anti-Mouse, Alexa Fluor 647, Clone: 2C9.G2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563523-Each-of-1 In Stock ₹ 16,085.28

BDB563523 - Each of 1

₹ 16,085.28

In Stock

Quantity

1

Base Price: ₹ 16,085.28

GST (18%): ₹ 2,895.35

Total Price: ₹ 18,980.63

Antigen

CD61

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Itgb3; Integrin beta-3; INGRB3; Platelet glycoprotein IIIa; GP3A; GPIIIa

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

2C9.G2

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse T-cell Hybridoma 2B4 Vitronectin Receptor

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 2C9.G2 monoclonal antibody specifically binds to the integrin β 3 chain (CD61), which associates with the integrin α v chain (CD51) to form the vitronectin receptor and with the α IIb chain (CD41) to form the gpIIb/IIIa complex
  • Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor
  • Leukocyte-endothelial adhesion is also mediated by the binding of α v β 3 integrin or vitronectin receptor to CD31 (PECAM-1)
  • In addition, interaction of the α v β 3 integrin with its ligands regulates the L-type Ca2+ channel in vascular smooth muscle cells, possibly mediating vasodilatory responses to injury
  • Soluble and insoluble 2C9.G2 mAb mimics the effect of the natural ligands in smooth muscle cells from rat cremaster arterioles
  • Furthermore, osteopontin, also named Eta-1, is a cytokine that binds to α v β 3
  • CD61 is expressed on platelets, activated T lymphocytes, polymorphonuclear granulocytes, and blastocysts
  • Cross-reactivity of mAb 2C9.G2 to rat mast cells and platelets has been observed by flow cytometric analysis
  • mAb 2C9.G2 has been demonstrated to block binding of rat and mouse cells to fibronectin.

Compare Similar Items

Show Difference

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BD Biosciences

BDB563523

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Antigen:
CD61

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Itgb3; Integrin beta-3; INGRB3; Platelet glycoprotein IIIa; GP3A; GPIIIa

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
2C9.G2

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse T-cell Hybridoma 2B4 Vitronectin Receptor

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB563526

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Antigen:
CD15s

Classification:
Monoclonal

Concentration:
__

Description:
Sialyl Lewis X

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
CSLEX1

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Membrane proteins from human tomach adenocarcinoma tissue

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB563529

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Antigen:
CD15s

Classification:
Monoclonal

Concentration:
__

Description:
Sialyl Lewis X

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
CSLEX1

Conjugate:
Brilliant Violet 510

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Membrane proteins from human tomach adenocarcinoma tissue

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD45

Classification:
Monoclonal

Concentration:
__

Description:
Pan Leukocyte, NHP-specific

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Rhesus Monkey

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
D058-1283

Conjugate:
Brilliant Violet 510

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Rhesus peripheral whole blood

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.