TER-119/Erythroid Cells Rat anti-Mouse, BUV395, Clone: TER-119, BD

Description

• The TER-119 antibody specifically binds to a 52 kDa molecule associated with glycophorin A on cells of the erythroid lineage in embryonic yolk sac, fetal liver, newborn liver, adult bone marrow, adult peripheral blood, and adult lymphoid organs
• The TER-119 antigen is expressed on erythroid cells from pro-erythroblast through mature erythrocyte stages, but not on cells with BFU-E or CFU-E activities
• The TER-119 epitope is not detected on hematopoietic stem cells, lymphoid cells, myeloid cells, or erythroleukemia lines
• The TER-119 mAb is a component of the “lineage cocktail” used in studies of hematopoietic progenitors to detect, or deplete cells committed to the hematopoietic lineages
• The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument
• With an Ex Max at 348 nmand an Em Max at 395nm, this dye has virtually no spillover into any other detector
• BD Horizon™ BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.