BDB564729

Nkx2.2 Mouse, Alexa Fluor 647, Clone: 74.5A5, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564729-Each-of-1 In Stock ₹ 26,309.70

BDB564729 - Each of 1

₹ 26,309.70

In Stock

Quantity

1

Base Price: ₹ 26,309.70

GST (18%): ₹ 4,735.746

Total Price: ₹ 31,045.446

Antigen

Nkx2.2

Classification

Monoclonal

Concentration

0.2mg/mL

Description

NKX2-2; NKX2B; Nkx2-2; Nkx-2.2; NK-2 homolog B; glycoprotein GP330

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Chicken, Human, Mouse, Rat

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

74.5A5

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Chicken Nkx2.2 Recombinant Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 74.5A5 monoclonal antibody specifically binds to Homeobox protein Nkx-2.2 (Nkx2.2), which is a transcription factor required for the differentiation of ventral neuronal populations in the central nervous system and endocrine cell populations in the pancreas and intestine
  • Within the pancreas, Nkx2.2 is expressed in many cell subsets and plays important roles in islet and β- cell differentiation and maturation
  • Mice with a homozygous disruption of the Nkx2-2 gene lack mature β cells and die shortly after birth with severe hyperglycemia
  • Similarly to the Nkx2.2-ablated mice, homozygous mutations in the human NKX2-2 gene have been described in diabetic patients and associated with the etiology of neonatal diabetes
  • The NKX2-2 gene is also a target of the Ewing sarcoma specific protein EWS-FLI
  • Nkx2.2 expression can be monitored in order to determine cell fate changes in cultures for the generation of human pluripotent stem cell-derived insulin-producing cells as well as oligodendrocyte progenitors.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB564729

--


Antigen:
Nkx2.2

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
NKX2-2; NKX2B; Nkx2-2; Nkx-2.2; NK-2 homolog B; glycoprotein GP330

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Chicken, Human, Mouse, Rat

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
74.5A5

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Chicken Nkx2.2 Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB564730

--


Antigen:
Nkx2.2

Classification:
Monoclonal

Concentration:
__

Description:
NKX2-2; NKX2B; Nkx2-2; Nkx-2.2; NK-2 homolog B; glycoprotein GP330

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Chicken, Human, Mouse, Rat

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
74.5A5

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Chicken Nkx2.2 Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB564732

--


Antigen:
CD148

Classification:
Monoclonal

Concentration:
__

Description:
DEP-1; DEP1; HPTP eta; HPTP-η; PTPRJ; R-PTP-eta; R-PTP-J; SCC1; p260

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
A3

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Activated human peripheral blood mononuclear cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB564736

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Antigen:
CD196

Classification:
Monoclonal

Concentration:
__

Description:
CCR6, BN-1, CKR-L3, DRY6, KY411, GPR-CY4, STRL22

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
140706

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Mouse CCR6-transfected Rat Cell Line

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.