BDB564820
CD365 (TIM-1) Mouse anti-Human, PE, Clone: 1D12, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564820-Each-of-1 | In Stock | ₹ 22,930.08 |
BDB564820 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,930.08
GST (18%): ₹ 4,127.414
Total Price: ₹ 27,057.494
Antigen
CD365
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human TIM-1 Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
1D12
Description
TIM1; TIM; TIMD1; TIMD-1; HAVCR1; HAVCR-1; HAVCR; KIM1; KIM-1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 1D12 monoclonal antibody specifically binds to CD365, the T-cell immunoglobulin mucin receptor 1 (TIM-1)
- TIM-1 is expressed on kidney epithelial cells, T cells, and some hematopoietic and non-hematopoietic cells
- CD365 (TIM-1) is a type 1 transmembrane glycoprotein that serves as a receptor for hepatitis A virus and is encoded by the HAVCR1 (Hepatitis A virus cellular receptor 1) gene
- TIM-1 also serves as a receptor for phosphatidylserine which is exposed on the surface of apoptotic cells
- TIM-1 can reportedly mediate the uptake of apoptotic cells through the recognition of phosphatidylserine and thus help maintain tissue homeostasis and self-tolerance
- TIM-1 is likewise known as Kidney injury molecule 1 (KIM-1)
- It is highly expressed by cancerous kidneys, and upregulated in the proximal tubular epithelium and shed into the urine during acute and chronic kidney injury
- CD365 (TIM-1) also functions as a costimulatory molecule for immune cells
- It is expressed by activated CD4+ T cells and regulates the effector functions (eg, enhanced cytokine production) and survival of differentiated T cells, including those mediating Th2-like immune responses
- Other ligands have been described for TIM-1 including TIM-4 and LMIR5 (also known as CD300b) which are expressed by myeloid cells
- With respect to disease associations, the HAVCR1 gene has been linked to asthma, allergy, and some autoimmune diseases.
Compare Similar Items
Show Difference
Antigen: CD365
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human TIM-1 Recombinant Protein
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 1D12
Description: TIM1; TIM; TIMD1; TIMD-1; HAVCR1; HAVCR-1; HAVCR; KIM1; KIM-1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD365
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human TIM-1 Recombinant Protein
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
1D12
Description:
TIM1; TIM; TIMD1; TIMD-1; HAVCR1; HAVCR-1; HAVCR; KIM1; KIM-1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: IL-23
Classification: Monoclonal
Conjugate: PerCP-Cyanine5.5
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse IL-23 Receptor Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: O78-1208
Description: Il23r; IL-23R; Interleukin 23 receptor
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
IL-23
Classification:
Monoclonal
Conjugate:
PerCP-Cyanine5.5
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse IL-23 Receptor Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
O78-1208
Description:
Il23r; IL-23R; Interleukin 23 receptor
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: Trop-2
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human BeWo (choriocarcinoma) Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 162-46
Description: GA733-1; TROP2; EGP-1; EGP1; GP50; M1S1; TACD2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
Trop-2
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human BeWo (choriocarcinoma) Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
162-46
Description:
GA733-1; TROP2; EGP-1; EGP1; GP50; M1S1; TACD2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD32
Classification: Monoclonal
Conjugate: Brilliant Violet 786
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: K562 or FcγRII+ L cell lines
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: FLI8.26
Description: CD32a,FcγRIIa, FCGR2A; CD32b, FcγRIIb, FCGR2B; CD32c, FcγRIIc, FCGR2C
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG2b κ
Antigen:
CD32
Classification:
Monoclonal
Conjugate:
Brilliant Violet 786
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
K562 or FcγRII+ L cell lines
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
FLI8.26
Description:
CD32a,FcγRIIa, FCGR2A; CD32b, FcγRIIb, FCGR2B; CD32c, FcγRIIc, FCGR2C
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG2b κ