BDB564931

CD53 Rat anti-Mouse, Alexa Fluor 647, Clone: OX-79, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB564931-Each-of-1 In Stock ₹ 17,009.33

BDB564931 - Each of 1

₹ 17,009.33

In Stock

Quantity

1

Base Price: ₹ 17,009.33

GST (18%): ₹ 3,061.679

Total Price: ₹ 20,071.009

Antigen

CD53

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Cd53: Ox-44; Tspan25; Tetraspanin-25

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgM κ

Applications

Flow Cytometry

Clone

OX-79

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide

Immunogen

BAB/14 mouse macrophage cell line RAW 264

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The OX-79 antibody reacts with CD53, a 35-45-kDa member of the Transmembrane 4-pass protein superfamily (TM4SF)
  • As in the human, mouse peripheral leukocytes express CD53 mRNA and protein, and erythrocytes and nonhematopoietic cells do not
  • However, the distribution of CD53 in the mouse and rat thymus differs from that in the human
  • In the mouse, most CD4+8- and major subsets of CD4- CD8- (double-negative) and CD4- CD8+ thymocytes express CD53, while most cortical CD4+ CD8+ (double-positive) thymocytes are CD53-low or CD53-negative
  • CD53 expression can be induced in double-positive thymocytes by cross-linking of their T-cell receptors with anti-TCR mAb or peptide-pulsed antigen-presenting cells
  • There is a strong correlation between positive selection of thymocytes and CD53 expression
  • Its association with CD2 and a tyrosine phosphatase in rat T lymphocytes and with CD19, CD21, HLA-DR, and other TM4SF proteins in human B lymphocytes suggests that CD53 is involved in leukocyte signal transduction.

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Antigen:
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Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cd53: Ox-44; Tspan25; Tetraspanin-25

Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
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Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide

Immunogen:
BAB/14 mouse macrophage cell line RAW 264

Quantity:
50 μg

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Concentration:
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Purification Method:
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Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
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Applications:
Flow Cytometry

Clone:
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Aqueous buffered solution containing ≤0.09% sodium azide.

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Formulation:
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