BDB565183

Siglec-F Rat anti-Mouse, APC-R700, Clone: E50-2440, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB565183-Each-of-1 In Stock ₹ 23,272.32

BDB565183 - Each of 1

₹ 23,272.32

In Stock

Quantity

1

Base Price: ₹ 23,272.32

GST (18%): ₹ 4,189.018

Total Price: ₹ 27,461.338

Antigen

Siglec-F

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Siglecf; Siglec5; sialic acid binding Ig-like lectin 5; SIGL5; Siglec-5

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

E50-2440

Conjugate

APC-R700

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen

Mouse Siglec-F and human IgG Fc recombinant fusion protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The E50-2440 monoclonal antibody specifically recognizes Siglec-F
  • Siglecs are the s ialic acid-binding immunoglobulin superfamily lectins defined in the human, each of which has a distinctive expression pattern in the hematopoietic system and at least some of which are known to mediate cell-cell interactions
  • Orthologous proteins of human Siglec-1 (Sialoadhesin or CD169), Siglec-2 (CD22), and Siglec-4 (myelin-associated glycoprotein) have been characterized in the mouse
  • Human Siglec-3 (CD33) and Siglecs-5 through -10 are encoded by a cluster of closely related genes, and each has two cytoplasmic ITIM (Immunoreceptor Tyrosine-based Inhibitory Motifs)
  • Similarly, mouse Siglec-F is encoded by a gene in a syntenic cluster in the mouse, and the protein has sialic acid-binding activity and an intracytoplasmic ITIM
  • Its expression pattern differs from those of the human Siglec-3-related proteins in that it is found on immature cells of the myelomonocytic lineage, with reduced expression on mature neutrophils and monocytes, and not on lymphoid cells
  • It has been proposed that mAb E50-2440 may be used for identification of immature myelomonocytic cells in the mouse.

Compare Similar Items

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BD Biosciences

BDB565183

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Antigen:
Siglec-F

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Siglecf; Siglec5; sialic acid binding Ig-like lectin 5; SIGL5; Siglec-5

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
E50-2440

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Mouse Siglec-F and human IgG Fc recombinant fusion protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB565184

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Antigen:
CD107a

Classification:
Monoclonal

Concentration:
__

Description:
LAMP1; LAMP-1; LAMPA; LGP120

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
H4A3

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Adult Adherent Peripheral Blood Cells

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB565185

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Antigen:
CD127

Classification:
Monoclonal

Concentration:
__

Description:
IL-7R; IL7R; IL7RA; IL-7Rα; IL-7R-alpha; Interleukin-7 Receptor alpha

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
HIL-7R-M21

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.

Immunogen:
Recombinant Human IL-7R

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD274

Classification:
Monoclonal

Concentration:
__

Description:
B7-H1; B7-H; PD-L1; PDL1; PDCD1 ligand 1; PDCD1L1; PDCD1LG1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MIH1

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human B7-H1 Transfected Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.