BDB565224
CD195 Mouse anti-Human, BUV395, Clone: 2D7/CCR5, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565224-Each-of-1 | In Stock | ₹ 32,752.00 |
BDB565224 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,752.00
GST (18%): ₹ 5,895.36
Total Price: ₹ 38,647.36
Antigen
CD195
Classification
Monoclonal
Conjugate
Brilliant Ultraviolet 395
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen
Human CCR5 Transfected Cell Line
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
2D7/CCR5
Description
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Description
- The 2D7/CCR5 monoclonal antibody specifically binds to the human chemokine receptor, CCR5
- CCR5 is also known as CD195
- CCR5 is a seven transmembrane-spanning G protein-associated molecule
- CCR5 belongs to the beta chemokine receptor family
- It is expressed on a subset of T lymphocytes (CD3+CD45RO+CD95+)
- CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation
- It signals a response to at least three chemokines: Regulated upon Activation Normal T-cell Expressed and Secreted (RANTES), Macrophage Inflammatory Protein-1 (MIP-1) and Monocyte Chemoattractant Protein 2 (MCP-2)
- Additionally, CCR5 has been found to be a coreceptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission
- Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele, demonstrate resistance to HIV infection
- This antibody has been shown to block ligand and gp120 binding
- It is also able to neutralize HIV infection
- The antibody was conjugated to BD Horizon BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument
- With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector
- BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.
Compare Similar Items
Show Difference
Antigen: CD195
Classification: Monoclonal
Conjugate: Brilliant Ultraviolet 395
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen: Human CCR5 Transfected Cell Line
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 2D7/CCR5
Description: CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD195
Classification:
Monoclonal
Conjugate:
Brilliant Ultraviolet 395
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen:
Human CCR5 Transfected Cell Line
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
2D7/CCR5
Description:
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD79B
Classification: Monoclonal
Conjugate: Brilliant Blue 515 (BB515)
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Cell membranes from human B-prol ymphocytic leukemia (B-PLL) cells
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 3A2-2E7
Description: Igβ/SN8/3A2-2E7-1F5
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD79B
Classification:
Monoclonal
Conjugate:
Brilliant Blue 515 (BB515)
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Cell membranes from human B-prol ymphocytic leukemia (B-PLL) cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
3A2-2E7
Description:
Igβ/SN8/3A2-2E7-1F5
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Terminal Transferase (TdT)
Classification: Monoclonal
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Purified Human TdT
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry, Immunocytochemistry
Clone: E17-1519
Description: TdT; DNTT; Terminal transferase; Terminal addition enzyme
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
Terminal Transferase (TdT)
Classification:
Monoclonal
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Purified Human TdT
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
E17-1519
Description:
TdT; DNTT; Terminal transferase; Terminal addition enzyme
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Terminal Transferase (TdT)
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Purified Human TdT
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry, Immunocytochemistry
Clone: E17-1519
Description: TdT; DNTT; Terminal transferase; Terminal addition enzyme
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
Terminal Transferase (TdT)
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Purified Human TdT
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
E17-1519
Description:
TdT; DNTT; Terminal transferase; Terminal addition enzyme
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ