BDB565368

CD115 Rat anti-Human, PE, Clone: 9-4D2-1E4, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565368-Each-of-1 In Stock ₹ 30,801.60

BDB565368 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

CD115

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human CD115 Transfected Cell Line

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

9-4D2-1E4

Description

CSF-1R; CSF1R; C-FMS; FMS; FIM2

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The 9-4D2-1E4 monoclonal antibody specifically binds to CD115 which is also known as Colony stimulating factor 1 receptor (CSF-1R) or Macrophage colony-stimulating factor 1 receptor (M-CSFR)
  • This type I transmembrane glycoprotein is a receptor tyrosine kinase (RTK) that belongs to the Ig superfamily
  • It is expressed on a variety of cells including those committed to the mononuclear phagocyte lineage, such as, monocytes, macrophages, and osteoclasts
  • CSF-1 binds to and signals through CSF-1R homodimers which undergo tyrosine autophosphorylation and transduce downstream signaling pathways resulting in cytoskeletal reorganization and gene expression
  • CSF-1R activation stimulates the proliferation, differentiation, and survival of cells within the mononuclear phagocyte system
  • Acting through CD115, CSF-1 induces macrophage spreading and motility, and in combination with RANKL, CSF-1 drives the differentiation of mononuclear phagocytes to become osteoclasts
  • Interleukin-34 (IL-34) is another ligand for CD115 that can induce similar, as well as, some different biological responses by CD115-positive target cells.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB565368

--


Antigen:
CD115

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human CD115 Transfected Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
9-4D2-1E4

Description:
CSF-1R; CSF1R; C-FMS; FMS; FIM2

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB565369

--


Antigen:
Ly-6G

Classification:
Monoclonal

Conjugate:
APC-H7

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Ly-6G-transfected EL4J cell line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with APC-H7 under optimum conditions, and unconjugated antibody and APC-H7 were removed.

Applications:
Flow Cytometry

Clone:
1A8

Description:
__

Host Species:
Rat

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB565371

--


Antigen:
CD45R/B220

Classification:
Monoclonal

Conjugate:
APC-H7

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Mouse Abelson Leukemia Virus-Induced pre-B tumor cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with APC-H7 under optimum conditions, and unconjugated antibody and APC-H7 were removed.

Applications:
Flow Cytometry

Clone:
RA3-6B2

Description:
Vol. Per test: 5μL

Host Species:
Rat

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB565378

--


Antigen:
IgG2b, κ

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to Alexa Fluor™ 647 under optimum conditions and unreacted Alexa Fluor™ 647 was removed.

Applications:
Flow Cytometry

Clone:
27-35

Description:
__

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
__

Isotype:
IgG2b κ