BDB565428

CD81 Mouse anti-Human, PE-CF594, Clone: JS-81, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565428-Each-of-1 In Stock ₹ 34,395.12

BDB565428 - Each of 1

₹ 34,395.12

In Stock

Quantity

1

Base Price: ₹ 34,395.12

GST (18%): ₹ 6,191.122

Total Price: ₹ 40,586.242

Antigen

CD81

Classification

Monoclonal

Conjugate

PE-CF594

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Canine, Human, Rabbit

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

JS-81

Description

TAPA1; Tetraspanin-28; Tspan-28; TSPAN28; CVID6; S5.7; M38

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The JS-81 monoclonal antibody specifically binds to CD81, which is also known as, Target of the antiproliferative antibody 1 (TAPA1, TAPA-1), or Tetraspanin-28 (Tspan-28/TSPAN28)
  • CD81 is an ∽26 kDa transmembrane protein that belongs to the tetraspanin (TM4SF) family
  • It is involved in cell growth and signal transduction
  • CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin
  • In hematopoietic cells, the CD81 antigen is expressed on B and T lymphocytes, NK cells, thymocytes, eosinophils, germinal center follicular dendritic cells, and to a variable extent on monocytes
  • The CD81 antigen is not expressed on neutrophils, platelets, or erythrocytes
  • CD81-specific antibodies have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas
  • They are also reported to induce homotypic cell aggregation
  • Immunoprecipitation studies reveal that CD81 is a component of a multimolecular complex of CD19, CD21, and CD225 that is involved in the activation and control of B cell growth
  • This antibody is conjugated to BD Horizon PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
  • PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
  • Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg, 610/20-nm filter).

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Antigen:
CD81

Classification:
Monoclonal

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Canine, Human, Rabbit

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
JS-81

Description:
TAPA1; Tetraspanin-28; Tspan-28; TSPAN28; CVID6; S5.7; M38

Host Species:
Mouse

Quantity:
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Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Classification:
Monoclonal

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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Canine, Human, Rabbit

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
JS-81

Description:
TAPA1; Tetraspanin-28; Tspan-28; TSPAN28; CVID6; S5.7; M38

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