BDB565775
LAG-3 (CD223) Mouse anti-Human, APC-R700, Clone: T47-530, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565775-Each-of-1 | In Stock | ₹ 15,229.68 |
BDB565775 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,229.68
GST (18%): ₹ 2,741.342
Total Price: ₹ 17,971.022
Antigen
LAG-3 (CD223)
Clone
T47-530
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Classification
Monoclonal
Conjugate
APC-R700
Gene Alias
LAG3, CD223, FDC, Lymphocyte activation gene 3 protein, Protein FDC
Immunogen
Human LAG-3 Recombinant Protein
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The T47-530 specifically recognizes the Lymphocyte Activation Gene 3 (LAG-3) protein which is also known as, Protein FDC, or CD223
- LAG-3 is a ñ70 kDa type I transmembrane glycoprotein that belongs to the Ig superfamily and exhibits homology to CD4
- LAG-3 is expressed on NK cells, regulatory T cells, and activated conventional T cells with higher expression found on CD8+ T cells compared with CD4+ T cells
- LAG-3 is an activation induced cell surface molecule that like CD4, binds MHC class II molecules, but with much higher affinity
- This may enable LAG-3 to act as a negative competitor of CD4 for MHC class II ligand binding
- LAG-3 may associate with the TCR-CD3 complex to downregulate TCR signal transduction and T cell clonal expansion
- In contrast, LAG-3-induced signaling may promote dendritic cell activation
- This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
- APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
- This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45nm filter)
- APC-R700 is a tandem fluorochrome that combines APC with R700, a proprietary organic dye
- This dye has been developed exclusively by BD Biosciences as a brighter alternative to Alexa Fluor™ 700
- Due to similar excitation and emission properties, APC-R700 and Alexa Fluor™ 700 cannot be used simultaneously.
Compare Similar Items
Show Difference
Antigen: LAG-3 (CD223)
Clone: T47-530
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: APC-R700
Gene Alias: LAG3, CD223, FDC, Lymphocyte activation gene 3 protein, Protein FDC
Immunogen: Human LAG-3 Recombinant Protein
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
LAG-3 (CD223)
Clone:
T47-530
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
APC-R700
Gene Alias:
LAG3, CD223, FDC, Lymphocyte activation gene 3 protein, Protein FDC
Immunogen:
Human LAG-3 Recombinant Protein
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Cβ1 TCR
Clone: JOVI.1
Formulation: __
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Classification: Monoclonal
Conjugate: PE
Gene Alias: __
Immunogen: __
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Refrigerate (2 to 8°C)
Antigen:
Cβ1 TCR
Clone:
JOVI.1
Formulation:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Classification:
Monoclonal
Conjugate:
PE
Gene Alias:
__
Immunogen:
__
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Refrigerate (2 to 8°C)
Antigen: IgG2,λ
Clone: Ha4/8
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: __
Isotype: IgG2 λ
Classification: Monoclonal
Conjugate: APC-R700
Gene Alias: __
Immunogen: Keyhole limpet hemocyanin
Quantity: 0.1 mg
Primary or Secondary: __
Content And Storage: Store undiluted at 4°C. Do not freeze. Protect from light.
Antigen:
IgG2,λ
Clone:
Ha4/8
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
__
Isotype:
IgG2 λ
Classification:
Monoclonal
Conjugate:
APC-R700
Gene Alias:
__
Immunogen:
Keyhole limpet hemocyanin
Quantity:
0.1 mg
Primary or Secondary:
__
Content And Storage:
Store undiluted at 4°C. Do not freeze. Protect from light.
Antigen: CD152
Clone: UC10-4F10-11
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: APC-R700
Gene Alias: __
Immunogen: Mouse CTLA-4 IgG2a Fusion
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD152
Clone:
UC10-4F10-11
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
APC-R700
Gene Alias:
__
Immunogen:
Mouse CTLA-4 IgG2a Fusion
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.