BDB565785

AID Rat anti-Human, Alexa Fluor 647, Clone: EK2-5G9, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565785-Each-of-1 In Stock ₹ 24,427.38

BDB565785 - Each of 1

₹ 24,427.38

In Stock

Quantity

1

Base Price: ₹ 24,427.38

GST (18%): ₹ 4,396.928

Total Price: ₹ 28,824.308

Antigen

AID

Classification

Monoclonal

Concentration

0.2mg/mL

Description

AID; ARP2; CDA2; HEL-S-284; HIGM2; Cytidine aminohydrolase

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry, Immunofluorescence, Immunocytochemistry

Clone

EK2-5G9

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human AID (185-198) Peptide

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The EK2-5G9 monoclonal antibody specifically binds to human Activation-induced cytidine deaminase (AICDA), also known as AID, or Single-stranded DNA cytosine deaminase
  • AID is an enzyme that preferentially acts upon certain DNA sequence motifs, such as those located in immunoglobulin variable regions, to induce cytidine-to-uracil mutations
  • AID-induced mutations initiate both somatic hypermutation (SHM) and class switch recombination (CSR) of the immunoglobulin genes in activated B cells during immune responses
  • While essential for immunoglobulin gene diversification, dysregulated AID activity can result in genomic instability and oncogenic transformation
  • Originally thought to be B-cell specific, AID now appears to be abnormally expressed in several epithelial cancers
  • AID may also play roles in DNA demethylation.

Compare Similar Items

Show Difference

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BD Biosciences

BDB565785

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Antigen:
AID

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
AID; ARP2; CDA2; HEL-S-284; HIGM2; Cytidine aminohydrolase

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunofluorescence, Immunocytochemistry

Clone:
EK2-5G9

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human AID (185-198) Peptide

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB565786

--


Antigen:
IgG1

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ighg1; Immunoglobulin heavy constant gamma 1; Igh-4

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
A85-1

Conjugate:
Brilliant Violet 711

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Pooled IgG1

Quantity:
50 μg

Primary or Secondary:
Secondary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB565787

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Antigen:
F4/80

Classification:
Monoclonal

Concentration:
__

Description:
__

Host Species:
Rat

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
T45-2342

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Mouse F4/80 Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon APC-R700 under optimum conditions, and unconjugated antibody and free BD Horizon APC-R700 were removed.

Img

BD Biosciences

BDB565788

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Antigen:
AhR

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Description:
__

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
T49-550

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human AhR Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to Alexa Fluor 488 under optimum conditions, and unreacted Alexa Fluor 488 was removed.