BDB565831
C-Peptide Mouse, Alexa Fluor 647, Clone: U8-424, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565831-Each-of-1 | In Stock | ₹ 26,299.50 |
BDB565831 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,299.50
GST (18%): ₹ 4,733.91
Total Price: ₹ 31,033.41
Antigen
C-Peptide
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
Human C-Peptide
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
Clone
U8-424
Conjugate
Alexa Fluor 647
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human, Mouse, Rat
Isotype
IgG1 κ
Description
- The U8-424 monoclonal antibody specifically binds to human, mouse, and rat C-Peptide, the connecting peptide that links the A- and B-chains in the proinsulin molecule
- The A- and B- chains and C-Peptide are encoded by the transcript of the INS gene and are produced by the β cells in the islets of Langerhans of the pancreas
- As the biosynthesis of insulin proceeds, the C-Peptide is cleaved from proinsulin to form the mature insulin hormone, which is composed of the A- and B-chains linked by 2 disulfide bonds
- Mature insulin and C-Peptide are stored i n granules in the β cells and are released to the blood in response to metabolic signals such as glucose, the amino acids arginine and leucine, and acetylcholine
- As a result, C-Peptide is released into the blood stream in an equimolar amount to insulin; the serum level of C- Peptide correlates with pancreatic β cell function and the amount of insulin being produced
- The expression of C-Peptide can be used to monitor the pancreatic differentiation of pluripotent stem cells
- Insulin is an evolutionarily conserved peptide hormone that binds to receptors on target cells (primarily adipose and muscle) to promote the absorption of glucose from the blood, thus regulating fat and carbohydrate metabolism
- C-Peptide itself binds to many cell types, independently of the insulin receptor, and initiates several intracellular signaling cascades.
Compare Similar Items
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Antigen: C-Peptide
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Human C-Peptide
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
Clone: U8-424
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Antigen:
C-Peptide
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Human C-Peptide
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
Clone:
U8-424
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Antigen: Ingegrin αvβ5
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse fibroblasts expressing αvβ5
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: ALULA
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Isotype: IgG2b κ
Antigen:
Ingegrin αvβ5
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse fibroblasts expressing αvβ5
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
ALULA
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Antigen: CD103
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Mouse Intestinal Epithelial Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M290
Conjugate: PE-CF594
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD103
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Mouse Intestinal Epithelial Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M290
Conjugate:
PE-CF594
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: F4/80
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse F4/80 Recombinant Protein
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to Alexa Fluor™ 647 under optimum conditions and unreacted Alexa Fluor™ 647 was removed.
Applications: Flow Cytometry
Clone: T45-2342
Conjugate: Alexa Fluor 647
Host Species: Rat
Purification Method: __
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
F4/80
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse F4/80 Recombinant Protein
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to Alexa Fluor™ 647 under optimum conditions and unreacted Alexa Fluor™ 647 was removed.
Applications:
Flow Cytometry
Clone:
T45-2342
Conjugate:
Alexa Fluor 647
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ