BDB566258
CD95 Mouse anti-Human, Brilliant Violet 421, Clone: DX2, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566258-Each-of-1 | In Stock | ₹ 18,309.84 |
BDB566258 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,309.84
GST (18%): ₹ 3,295.771
Total Price: ₹ 21,605.611
Antigen
CD95
Clone
DX2
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Classification
Monoclonal
Conjugate
Brilliant Violet 421
Gene Alias
APO-1, FAS, TNFRSF6, APT1, ALPS1A, FAS1, FASTM, FASLG receptor
Immunogen
Human CD95-transfected L Cells
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The DX2 monoclonal antibody specifically binds to the human Fas antigen (also called APO-1)
- This 45 kDa transmembrane cell surface molecule was designated as CD95 at the Fifth HLDA Workshop
- Fas is a member of the TNF-receptor superfamily and is also known as Tumor necrosis factor receptor superfamily member 6 (TNFRSF6)
- It is expressed on a variety of normal and neoplastic cells including activated T and B lymphocytes and some undifferentiated thymocytes
- The Fas/CD95 antigen is a polypeptide that plays a role in the programmed sequence of events leading to cell death, termed apoptosis
- The DX2 clone specifically reacts with murine L cells, murine L1210 leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines
- Crosslinking CD95 with DX2 antibody delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen
- The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
- With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
- BD Horizon™ BV421conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
- Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
- Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
Compare Similar Items
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Antigen: CD95
Clone: DX2
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: APO-1, FAS, TNFRSF6, APT1, ALPS1A, FAS1, FASTM, FASLG receptor
Immunogen: Human CD95-transfected L Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD95
Clone:
DX2
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
APO-1, FAS, TNFRSF6, APT1, ALPS1A, FAS1, FASTM, FASLG receptor
Immunogen:
Human CD95-transfected L Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD107A
Clone: H4A3
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: LAMP1, LAMP-1, LAMPA, LGP120
Immunogen: Human Adult Adherent Peripheral Blood Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD107A
Clone:
H4A3
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
LAMP1, LAMP-1, LAMPA, LGP120
Immunogen:
Human Adult Adherent Peripheral Blood Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD54
Clone: HA58
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: ICAM-1; intercellular adhesion molecule 1; BB2; P3.58
Immunogen: IFN-γ-treated BM314 colonic carcinoma cells
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV421 under optimum conditions and unconjugated antibody and free BD Horizon™ BV421 were removed.
Antigen:
CD54
Clone:
HA58
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
ICAM-1; intercellular adhesion molecule 1; BB2; P3.58
Immunogen:
IFN-γ-treated BM314 colonic carcinoma cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV421 under optimum conditions and unconjugated antibody and free BD Horizon™ BV421 were removed.
Antigen: CD80
Clone: L307.4 (also known as L307)
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ, C3H/Bi IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: B7.1; B7-1; Activation B7-1 antigen; B7; BB1; CD28LG; CD28LG1; LAB7
Immunogen: Human B7-transfected L cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV421 under optimum conditions and unconjugated antibody and free BD Horizon™ BV421 were removed.
Antigen:
CD80
Clone:
L307.4 (also known as L307)
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ, C3H/Bi IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
B7.1; B7-1; Activation B7-1 antigen; B7; BB1; CD28LG; CD28LG1; LAB7
Immunogen:
Human B7-transfected L cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV421 under optimum conditions and unconjugated antibody and free BD Horizon™ BV421 were removed.