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BDB566297

CD103 Rat anti-Mouse, Brilliant Violet 421, Clone: M290, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB566297-Each-of-1 In Stock ₹ 15,298.13

BDB566297 - Each of 1

₹ 15,298.13

In Stock

Quantity

1

Base Price: ₹ 15,298.13

GST (18%): ₹ 2,753.663

Total Price: ₹ 18,051.793

Antigen

CD103

Clone

M290

Conjugate

Brilliant Violet 421

Gene Alias

Itgae, Integrin alpha-E, αE, alpha-E1, ITAE, Integrin αIEL chain, aM290

Immunogen

Mouse Intestinal Epithelial Cells

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Description

  • The M290 antibody specifically binds to CD103, the α chain of αIELβ7 integrin
  • CD103 has a unique and fairly restricted tissue distribution
  • It is expressed on almost all intestinal intraepithelial lymphocytes (IEL), on dendritic epidermal T cells (DEC), on subpopulations of peripheral T cells, and on distinct subsets of fetal, neonatal, and adult thymocytes
  • E-cadherin is the epithelial-cell ligand for αIELβ7 integrin
  • The ordered expression of αIEL during thymocyte development (which occurs under the influence of the thymic epithelium), the high level of expression of αIEL on those peripheral T cells found in epithelial tissues (IEL and DEC), and the expression of CD103 on a subset of CD8+ lymphocytes responding to allogeneic epithelial cells suggest that αIELβ7 integrin may have a common role in the interactions of T lymphocytes with epithelia during T-cell maturation and effector functions
  • CD103 is thought to play a role in allograft rejection
  • The M290 antibody is reported to efficiently inhibit αIELβ7-mediated adhesion in in vitro /assays
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
  • BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
  • Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
  • Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.

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BD Biosciences

BDB566297

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Antigen:
CD103
Clone:
M290
Conjugate:
Brilliant Violet 421
Gene Alias:
Itgae, Integrin alpha-E, αE, alpha-E1, ITAE, Integrin αIEL chain, aM290
Immunogen:
Mouse Intestinal Epithelial Cells
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ

Img

BD Biosciences

BDB566298

--

Antigen:
CD150
Clone:
Q38-480
Conjugate:
Brilliant Violet 421
Gene Alias:
SLAM; Slamf1; Signaling lymphocytic activation molecule family member 1
Immunogen:
Mouse CD150 Recombinant Protein
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV421 under optimum conditions and unconjugated antibody and free BD Horizon™ BV421 were removed.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ

Img

BD Biosciences

BDB566300

--

Antigen:
CD127
Clone:
SB/199
Conjugate:
Brilliant Violet 421
Gene Alias:
Interleukin-7 receptor alpha chain, IL-7R alpha, IL-7RA, IL-7Rα, Il7r
Immunogen:
BALB/c mouse pre-B cell line 1A9
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ

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BD Biosciences

BDB566305

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Antigen:
PVR (CD155)
Clone:
TX24 (also known as TX-24)
Conjugate:
Alexa Fluor 647
Gene Alias:
Poliovirus receptor, HVED, Nectin-like protein 5, NECL5, NECL-5, PVS, TAGE4
Immunogen:
Human PVR Transfected Cell Line
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a