BDB566315
IREM-2 (CD300e) Mouse anti-Human, Alexa Fluor 647, Clone: UP-H1, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566315-Each-of-1 | In Stock | ₹ 24,299.04 |
BDB566315 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,299.04
GST (18%): ₹ 4,373.827
Total Price: ₹ 28,672.867
Antigen
IREM-2 (CD300e)
Clone
UP-H1
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Gene Alias
IREM2, CD300E, CD300LE, CLM2, CLM-2, CMRF35-A5, PIgR-2, LMIR6
Immunogen
Human IREM-2 Transfected Cell Line
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The UP-H1 monoclonal antibody recognizes Immune receptor expressed by myeloid cells 2 (IREM-2) which is also known as CD300 antigen like family member E (CD300e), CMRF35-like molecule 2 (CLM2), or Polymeric immunoglobulin receptor 2 (PIgR2)
- IREM-2 is a 34 kDa type I transmembrane glycoprotein which belongs to the CMFRF35 subfamily of the immunoglobulin (Ig) superfamily
- IREM-2 is expressed on monocytes, macrophages and myeloid dendritic cells (mDCs), but not on lymphoid dendritic cells or granulocytes
- IREM-2 associates with DAP-12, an ITAM-containing adapter molecule, which provides activating signals
- Crosslinking of IREM-2 leads to intracellular calcium mobilization, release of proinflammatory cytokines such as TNF, and increased expression of activation markers on monocytes and mDCs
- IREM-2 activation of mDCs can reportedly enhance the alloreactive response of naive T cells
- Alexa Fluor™ 647 conjugates are highly photostable and remain fluorescent over a broad pH range
- The excitation and emission maxima are nearly identical to those of APC
- However, APC tends to be brighter while Alexa Fluor™ 647 is more optimal for intracellular applications
- This fluorochrome exhibits uncommon photostability, making it an ideal choice for use in fluorescence microscopy
- Due to nearly identical excitation and emission properties but different spillover characteristics, APC and Alexa Fluor™ 647 cannot be used simultaneously.
Compare Similar Items
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Antigen: IREM-2 (CD300e)
Clone: UP-H1
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Gene Alias: IREM2, CD300E, CD300LE, CLM2, CLM-2, CMRF35-A5, PIgR-2, LMIR6
Immunogen: Human IREM-2 Transfected Cell Line
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
IREM-2 (CD300e)
Clone:
UP-H1
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Gene Alias:
IREM2, CD300E, CD300LE, CLM2, CLM-2, CMRF35-A5, PIgR-2, LMIR6
Immunogen:
Human IREM-2 Transfected Cell Line
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD4
Clone: SK3 (also known as Leu3a)
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: PerCP-Cyanine5.5
Gene Alias: L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Immunogen: Human Peripheral Blood T Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD4
Clone:
SK3 (also known as Leu3a)
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
PerCP-Cyanine5.5
Gene Alias:
L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Immunogen:
Human Peripheral Blood T Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD4
Clone: SK3 (also known as Leu3a)
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: PE-CF594
Gene Alias: L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Immunogen: Human Peripheral Blood T Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD4
Clone:
SK3 (also known as Leu3a)
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
PE-CF594
Gene Alias:
L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Immunogen:
Human Peripheral Blood T Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD4
Clone: SK3 (also known as Leu3a)
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Gene Alias: L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Immunogen: Human Peripheral Blood T Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD4
Clone:
SK3 (also known as Leu3a)
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Gene Alias:
L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Immunogen:
Human Peripheral Blood T Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.