BDB566382
CD317 (BST2) Mouse anti-Human, Rhesus, Baboon, Cynomolgus, Brilliant Violet 421, Clone: Y129 (also known as HM1.24), BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566382-Each-of-1 | In Stock | ₹ 17,454.24 |
BDB566382 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,454.24
GST (18%): ₹ 3,141.763
Total Price: ₹ 20,596.003
Antigen
CD317 (BST2)
Clone
Y129 (also known as HM1.24)
Conjugate
Brilliant Violet 421
Gene Alias
BST2, BST-2, bone marrow stromal antigen 2, HM1.24 antigen, Tetherin
Immunogen
Human KPC-32 Plasma Cell Line
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype
IgG2a κ
Description
- The Y129 monoclonal antibody specifically binds to CD317 which is also known as Bone marrow stromal antigen 2 (BST2)
- CD317 is a type II transmembrane glycoprotein that belongs to the Tetherin family
- CD317 is an interferon (IFN)-induced protein that is expressed on monocytes, granulocytes, dendritic cells, B lymphoblasts, plasma cells, T cells, natural killer (NK) cells, stromal cells and myeloma cells
- CD317 is expressed by nonhematopoietic cells including cells within solid tumors derived from breast, lung and kidney
- CD317 may be involved in the interactions between bone marrow stromal cells and lymphocytes
- It is likewise known as Tetherin and reportedly blocks the release of some enveloped viruses by tethering virions to infected cell membranes
- CD317 stimulates signaling by CD85g (ILT7) and may provide negative feedback for interferon (IFN) production by plasmacytoid dendritic cells during viral infections
- The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
- BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
- BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
- Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
- Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
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Antigen: CD317 (BST2)
Clone: Y129 (also known as HM1.24)
Conjugate: Brilliant Violet 421
Gene Alias: BST2, BST-2, bone marrow stromal antigen 2, HM1.24 antigen, Tetherin
Immunogen: Human KPC-32 Plasma Cell Line
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG2a κ
Antigen:
CD317 (BST2)
Clone:
Y129 (also known as HM1.24)
Conjugate:
Brilliant Violet 421
Gene Alias:
BST2, BST-2, bone marrow stromal antigen 2, HM1.24 antigen, Tetherin
Immunogen:
Human KPC-32 Plasma Cell Line
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG2a κ
Antigen: CD181 (CXCR1)
Clone: U45-632
Conjugate: PE
Gene Alias: Il8ra,Cxcr1,C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, IL-8R A
Immunogen: Mouse CD181 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
CD181 (CXCR1)
Clone:
U45-632
Conjugate:
PE
Gene Alias:
Il8ra,Cxcr1,C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, IL-8R A
Immunogen:
Mouse CD181 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Antigen: CD118 (LIFR)
Clone: 12D3
Conjugate: PE
Gene Alias: __
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Refrigerate (2 to 8°C)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: __
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD118 (LIFR)
Clone:
12D3
Conjugate:
PE
Gene Alias:
__
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Refrigerate (2 to 8°C)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD68
Clone: FA/11 (also known as FA-11, FA11)
Conjugate: Brilliant Violet 421
Gene Alias: __
Immunogen: __
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Refrigerate (2 to 8°C)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: __
Host Species: Rat
Purification Method: __
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD68
Clone:
FA/11 (also known as FA-11, FA11)
Conjugate:
Brilliant Violet 421
Gene Alias:
__
Immunogen:
__
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Refrigerate (2 to 8°C)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
__
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ