BDB566990
ICOS (CD278) Armenian Hamster, anti-Human, R718, Clone: C398.4A, BD Horizon™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566990-Each-of-1 | In Stock | ₹ 25,276.00 |
BDB566990 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,276.00
GST (18%): ₹ 4,549.68
Total Price: ₹ 29,825.68
Antigen
ICOS (CD278)
Classification
Monoclonal
Conjugate
R718
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
Refrigerate Upon Arrival
Applications
Flow Cytometry
Clone
C398.4A
Host Species
Armenian Hamster
Regulatory Status
RUO
Target Species
Human
Form
Liquid
Description
- The C398.4A monoclonal antibody specifically binds to Inducible Costimulator (ICOS), which is also known as, CD278, Activation-inducible lymphocyte immunomediatory molecule (AILIM), or H4
- ICOS is a type I transmembrane glycoprotein that forms a disulfide-linked homodimer and belongs to the CD28 family within the Ig superfamily
- ICOS is expressed on either CD4+ or CD8+ single-positive mature thymocytes, T cells, or subsets of Innate Lymphoid Cells (ILC)
- Its expression is upregulated on activated T lymphocytes
- ICOS is a costimulatory receptor that can bind to the B7-H2 ligand (CD275, ICOS-L) that is expressed on B cells, monocytes, macrophages, dendritic cells, and endothelial cells
- ICOS plays a critical role in many types of T cell-dependent immunity
- In the case of humoral immunity, for example, ICOS signaling is critical for the differentiation of T follicular helper (Tfh) cells and development of germinal centers
- Although C398.4A was generated against mouse ICOS, this antibody reportedly crossreacts with human, rhesus, and rat ICOS.
Compare Similar Items
Show Difference
Antigen: ICOS (CD278)
Classification: Monoclonal
Conjugate: R718
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: Refrigerate Upon Arrival
Applications: Flow Cytometry
Clone: C398.4A
Host Species: Armenian Hamster
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Antigen:
ICOS (CD278)
Classification:
Monoclonal
Conjugate:
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Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
Refrigerate Upon Arrival
Applications:
Flow Cytometry
Clone:
C398.4A
Host Species:
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Regulatory Status:
RUO
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Human
Form:
Liquid
Antigen: CD80 (B7-1)
Classification: Monoclonal
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Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Applications: Flow Cytometry
Clone: 2D10.4 (also known as 2D10)
Host Species: Mouse
Regulatory Status: RUO
Target Species: Human
Form: __
Antigen:
CD80 (B7-1)
Classification:
Monoclonal
Conjugate:
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Quantity:
100 Tests
Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Applications:
Flow Cytometry
Clone:
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__
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Applications: Flow Cytometry
Clone: MAR-1 (also known as MAR1)
Host Species: Armenian Hamster
Regulatory Status: RUO
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Antigen:
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Quantity:
1 x 100 μg
Primary or Secondary:
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Applications:
Flow Cytometry
Clone:
MAR-1 (also known as MAR1)
Host Species:
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Primary or Secondary: Primary
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Flow Cytometry
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Form:
__