BDB569241
CD8 Mouse anti-Human, RB545, Clone: RPA-T8, BD Horizon™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB569241-Each-of-1 | In Stock | ₹ 13,065.01 |
BDB569241 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,065.01
GST (18%): ₹ 2,351.702
Total Price: ₹ 15,416.712
Antigen
CD8
Classification
Monoclonal
Conjugate
RB545
Gene Alias
CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32
Immunogen
Human CD8a
Quantity
25 Tests
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Excitation/Emission
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications
Flow Cytometry
Clone
RPA-T8
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Gene ID (Entrez)
925
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype
IgG1 κ
Description
- The RPA-T8 monoclonal antibody specifically binds to CD8 alpha (CD8a)
- CD8a is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
- CD8a is expressed by the majority of thymocytes, by subpopulations of aβ T cells and γδ T cells and by some NK cells
- Cell surface CD8a is expressed either as a disulfide-linked homodimer (CD8aa) or as a heterodimer (CD8aβ) when disulfide-bonded to a CD8 beta chain (CD8β)
- CD8-positive aβ T cells coexpress both CD8aa homodimers and CD8aβ heterodimers whereas some γδ T cells and NK cells express CD8aa homodimers
- CD8 plays important roles in T cell activation and selection
- The extracellular IgSF domain of CD8a binds to a non-polymorphic determinant on HLA class I molecules (a3 domain) and enables CD8 to function as a co-receptor with MHC class I-restricted TCR during T cell recognition of antigen
- The cytoplasmic domain of CD8a associates with Lck, a Src family protein tyrosine kinase that is involved in intracellular signaling
- The RPA-T8 and HIT8a monoclonal antibodies are not cross-blocking
- This clone has been reported to react with a subset of peripheral blood lymphocytes, but not monocytes nor granuloyctes, of baboon and both rhesus and cynomolgus macaque monkey
- In general, a higher frequency of CD8+ and CD4+CD8+ lymphocytes are observed in non-human primates compared to normal human donors
- CD8 Monoclonal antibody specifically detects CD8 in Human samples
- It is validated for Flow Cytometry
Compare Similar Items
Show Difference
Antigen: CD8
Classification: Monoclonal
Conjugate: RB545
Gene Alias: CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32
Immunogen: Human CD8a
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Excitation/Emission: Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications: Flow Cytometry
Clone: RPA-T8
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 925
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype: IgG1 κ
Antigen:
CD8
Classification:
Monoclonal
Conjugate:
RB545
Gene Alias:
CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32
Immunogen:
Human CD8a
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications:
Flow Cytometry
Clone:
RPA-T8
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
925
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype:
IgG1 κ
Antigen: CD16
Classification: Monoclonal
Conjugate: RB545
Gene Alias: CD16;CD16A;FCGR3A;FcγRIIIA;FcRIIIa;CD16B;FCGR3B;FcγRIIIB;FcRIIIb
Immunogen: Human polymorphonuclear leukocytes
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Excitation/Emission: Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications: Flow Cytometry
Clone: 3G8
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype: IgG1 κ
Antigen:
CD16
Classification:
Monoclonal
Conjugate:
RB545
Gene Alias:
CD16;CD16A;FCGR3A;FcγRIIIA;FcRIIIa;CD16B;FCGR3B;FcγRIIIB;FcRIIIb
Immunogen:
Human polymorphonuclear leukocytes
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications:
Flow Cytometry
Clone:
3G8
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype:
IgG1 κ
Antigen: I-A, I-E
Classification: Monoclonal
Conjugate: Brilliant Ultraviolet 395
Gene Alias: H-2I; I-Ad, -Ed; I-Eb and I-Ek MHC class II alloantigens; Ia Ag; MHC II
Immunogen: BALB/c mouse epidermal Langerhans cells
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Excitation/Emission: __
Applications: Flow Cytometry
Clone: 2G9
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14961, 14969
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unconjugated antibody and free dye were removed.
Isotype: IgG2a κ
Antigen:
I-A, I-E
Classification:
Monoclonal
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
H-2I; I-Ad, -Ed; I-Eb and I-Ek MHC class II alloantigens; Ia Ag; MHC II
Immunogen:
BALB/c mouse epidermal Langerhans cells
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid
Excitation/Emission:
__
Applications:
Flow Cytometry
Clone:
2G9
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14961, 14969
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unconjugated antibody and free dye were removed.
Isotype:
IgG2a κ
Antigen: TIM-3 (CD366)
Classification: Monoclonal
Conjugate: Brilliant Violet 605
Gene Alias: CD366; HAVCR2; TIM3; T cell immunoglobulin mucin-3; TIMD-3; KIM-3
Immunogen: Human TIM-3
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Excitation/Emission: __
Applications: Flow Cytometry
Clone: 7D3
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84868
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unconjugated antibody and free dye were removed.
Isotype: IgG1 κ
Antigen:
TIM-3 (CD366)
Classification:
Monoclonal
Conjugate:
Brilliant Violet 605
Gene Alias:
CD366; HAVCR2; TIM3; T cell immunoglobulin mucin-3; TIMD-3; KIM-3
Immunogen:
Human TIM-3
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Excitation/Emission:
__
Applications:
Flow Cytometry
Clone:
7D3
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84868
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unconjugated antibody and free dye were removed.
Isotype:
IgG1 κ