BDB569261
IL-17A Mouse anti-Human, RB545, Clone: N49-653, BD Horizon™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB569261-Each-of-1 | In Stock | ₹ 35,764.08 |
BDB569261 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
IL-17A
Classification
Monoclonal
Conjugate
RB545
Gene Alias
IL17; IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Immunogen
Human IL-17A Recombinant Protein
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Excitation/Emission
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications
Flow Cytometry
Clone
N49-653
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Gene ID (Entrez)
3605
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype
IgG1 κ
Description
- Human IL-17A, also known as IL-17, is a proinflammatory cytokine that is encoded by the IL17A gene in chromosome 6
- IL-17A is produced as a disulfide-linked homodimer comprised of two mature 136-amino acid polypeptides
- It is a member of the IL-17 family of structurally related cytokines, designated IL-17A through IL-17F
- Activated memory T cells, especially Th17 cells (specialized IL-17A-producing CD4+ T cells distinct from Th1 and Th2 cells) produce IL-17 and provide protective immunity against pathogens
- Activated CD8+ T cells, γδT cells, NK cells and neutrophils can also be activated to produce IL-17A
- IL-17A binds to and exerts its biological activity through IL-17 receptors (IL-17R) that are expressed by a variety of target cells including fibroblasts, epithelial and endothelial cells, monocytes/macrophages and mast cells
- The ubiquitous IL-17R expression pattern may explain the broad tissue responsiveness to IL-17
- IL-17 induces stromal cells to secrete cytokines and chemokines involved in inflammatory and hematopoietic processes
- For example, IL-17 induces fibroblasts to produce IL-6, IL-8, G-CSF and express increased surface ICAM-1
- The N49-653 antibody reacts with human IL-17A
- IL-17A Monoclonal antibody specifically detects IL-17A in Human samples
- It is validated for Intracellular Staining (Flow Cytometry)
Compare Similar Items
Show Difference
Antigen: IL-17A
Classification: Monoclonal
Conjugate: RB545
Gene Alias: IL17; IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Immunogen: Human IL-17A Recombinant Protein
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Excitation/Emission: Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications: Flow Cytometry
Clone: N49-653
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 3605
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype: IgG1 κ
Antigen:
IL-17A
Classification:
Monoclonal
Conjugate:
RB545
Gene Alias:
IL17; IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Immunogen:
Human IL-17A Recombinant Protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications:
Flow Cytometry
Clone:
N49-653
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
3605
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype:
IgG1 κ
Antigen: IL-17A
Classification: Monoclonal
Conjugate: RB545
Gene Alias: IL17; IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Immunogen: Human IL-17A Recombinant Protein
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Excitation/Emission: Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications: Flow Cytometry
Clone: N49-653
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 3605
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype: IgG1 κ
Antigen:
IL-17A
Classification:
Monoclonal
Conjugate:
RB545
Gene Alias:
IL17; IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Immunogen:
Human IL-17A Recombinant Protein
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications:
Flow Cytometry
Clone:
N49-653
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
3605
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype:
IgG1 κ
Antigen: CD56 (NCAM-1)
Classification: Monoclonal
Conjugate: RB545
Gene Alias: NCAM1; NCAM-1; Neural cell adhesion molecule 1; NCAM; NKH1; MSK39
Immunogen: Human NK Cells
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Excitation/Emission: Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications: Flow Cytometry
Clone: B159
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 4684
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype: IgG1 κ
Antigen:
CD56 (NCAM-1)
Classification:
Monoclonal
Conjugate:
RB545
Gene Alias:
NCAM1; NCAM-1; Neural cell adhesion molecule 1; NCAM; NKH1; MSK39
Immunogen:
Human NK Cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications:
Flow Cytometry
Clone:
B159
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
4684
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype:
IgG1 κ
Antigen: CD56 (NCAM-1)
Classification: Monoclonal
Conjugate: RB545
Gene Alias: NCAM1; NCAM-1; Neural cell adhesion molecule 1; NCAM; NKH1; MSK39
Immunogen: Human NK Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Excitation/Emission: Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications: Flow Cytometry
Clone: B159
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 4684
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype: IgG1 κ
Antigen:
CD56 (NCAM-1)
Classification:
Monoclonal
Conjugate:
RB545
Gene Alias:
NCAM1; NCAM-1; Neural cell adhesion molecule 1; NCAM; NKH1; MSK39
Immunogen:
Human NK Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
Applications:
Flow Cytometry
Clone:
B159
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
4684
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Isotype:
IgG1 κ