BDB569269

CD123 (IL-3 Receptor α) Mouse anti-Human, RB545, Clone: 7G3, BD Horizon™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB569269-Each-of-1 In Stock ₹ 35,764.08

BDB569269 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

CD123 (IL-3 Receptor α)

Classification

Monoclonal

Conjugate

RB545

Gene Alias

IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Immunogen

Human IL-3Ra-transfected cells

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Excitation/Emission

Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications

Flow Cytometry

Clone

7G3

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

3563

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype

IgG2a κ

Description

  • The 7G3 monoclonal antibody specifically recognizes human CD123, the 70 kDa IL-3 Receptor α (IL-3Rα) chain
  • CD123 associates with CD131, the 120-140 kDa Common β chain to form the IL-3 Receptor Complex
  • CD131 is shared with the receptors for interleukins IL-5 and GM-CSF
  • IL-3Rα is expressed on hematopoietic progenitors and plays an important role in hematopoietic progenitor cell growth and differentiation
  • It is also expressed by mast cells, macrophages and a CD5+ B cell subset
  • This antibody has been reported to block the binding of 125I-IL-3 to high and low affinity IL-3 receptors
  • In functional experiments, this antibody was found to inhibit acute myeloid leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration
  • This antibody has been reported to be useful for immunoprecipitation, Western blot and immunofluorescent staining for flow cytometry
  • At the Fifth HLDA Workshop, the human IL-3 receptor was designated CD123
  • CD123 (IL-3 Receptor α) Monoclonal antibody specifically detects CD123 (IL-3 Receptor α) in Human samples
  • It is validated for Flow Cytometry

Compare Similar Items

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BD Biosciences

BDB569269

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Antigen:
CD123 (IL-3 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Immunogen:
Human IL-3Ra-transfected cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
7G3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3563

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG2a κ

Img

BD Biosciences

BDB569270

--


Antigen:
CD123 (IL-3 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Immunogen:
Human IL-3Ra-transfected cells

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
7G3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3563

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG2a κ

Img

BD Biosciences

BDB569271

--


Antigen:
CD197 (CCR7)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
BLR2; CC chemokine receptor 7; CMKBR7; EBI1; EVI1; Epstein-Barr virus induced gene 1; MIP-3 beta receptor

Immunogen:
Human CCR7 Transfected Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
2-L1-A

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
1236

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ

Img

BD Biosciences

BDB569274

--


Antigen:
CD69

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
AIM; CLEC2C; EA1; GP32/28; Leu23; MLR-3; VEA; BL-AC/P26

Immunogen:
Anti-μ stimulated human B lymphocytes

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
FN50 (also known as FN 50)

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
969

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ