BDB569291

Granzyme B Mouse anti-Human, RB545, Clone: GB11, BD Horizon™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB569291-Each-of-1 In Stock ₹ 14,433.97

BDB569291 - Each of 1

₹ 14,433.97

In Stock

Quantity

1

Base Price: ₹ 14,433.97

GST (18%): ₹ 2,598.115

Total Price: ₹ 17,032.085

Antigen

Granzyme B

Classification

Monoclonal

Conjugate

RB545

Gene Alias

GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT

Immunogen

Human Granzyme B

Quantity

25 Tests

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Excitation/Emission

Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications

Flow Cytometry

Clone

GB11

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

3002

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype

IgG1 κ

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Description

  • Description The GB11 antibody specifically reacts with human granzyme B, a serine protease of approximately 32 kDa
  • Granzyme B is stored in the granules of cytotoxic T lymphocytes and NK cells along with the pore-forming protein perforin
  • In the classic model of target cell lysis, perforins create holes in the target cell membrane allowing entrance of granzymes
  • Granzyme B has been shown to act on specific substrates including caspase-3, -7, -9, and -10 which in turn give rise to enzymes that mediate apoptosis
  • Granzyme B may also be involved in the hydrolysis of extracellular matrix components
  • Detectable levels of granzyme B have been detected in sera from healthy volunteers
  • The immunogen used to generate the GB11 hybridoma was human granzyme B isolated from an NK cell line
  • Granzyme B Monoclonal antibody specifically detects Granzyme B in Human samples
  • It is validated for Intracellular Staining (Flow Cytometry)

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB569291

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Antigen:
Granzyme B

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT

Immunogen:
Human Granzyme B

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
GB11

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3002

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ

Img

BD Biosciences

BDB569292

--


Antigen:
__

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
Anti-DNS; Anti-Dansyl; IgG2b kappa; Isotype Control (anti-Dansyl)

Immunogen:
__

Quantity:
0.1 mg

Primary or Secondary:
__

Target Species:
__

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
27-35

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG2b κ

Img

BD Biosciences

BDB569293

--


Antigen:
GLUT1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
GLUT; GLUT-1; SLC2A1; glucose transporter type 1, erythrocyte/brain

Immunogen:
Human Glucose Transporter GLUT1

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Excitation/Emission:
__

Applications:
Flow Cytometry, Control

Clone:
EPR3915

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6513

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG

Img

Fischer Scientific

BDB569294

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Antigen:
CD127

Classification:
Monoclonal

Conjugate:
Brilliant Violet 605

Gene Alias:
Interleukin-7 receptor alpha chain; IL-7R alpha; IL7RA; IL-7RA; IL-7Rα; Il7

Immunogen:
Mouse IL-7Rα-IgG1 Fusion Protein

Quantity:
0.1 mg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Excitation/Emission:
__

Applications:
Flow Cytometry

Clone:
A7R34

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16197

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unconjugated antibody and free dye were removed.

Isotype:
IgG2a κ