BDB610001
Ras Mouse, Unlabeled, Clone: 18, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610001-Each-of-1 | In Stock | ₹ 24,598.50 |
BDB610001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,598.50
GST (18%): ₹ 4,427.73
Total Price: ₹ 29,026.23
Antigen
Ras
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human Ras (Ha-ras) aa. 1-190
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Canine, Chicken, Human, Mouse, Rat
Isotype
IgG1 κ
Applications
Western Blot
Clone
18
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Description
- Ras and related proteins of the Ras superfamily play critical roles in the control of normal and neoplastic proliferation
- In mammalian cells there are four true Ras proteins (encoded by Ha- ras , N- ras , Ki- ras A, and Ki- ras B ) which, upon mutational activation, can function as independent oncogenes
- These proteins relay signals from tyrosine kinases at the plasma membrane which subsequently lead to the nucleus via a network of serine/threonine kinases
- The p21ras protein is active in its GTP-bound state
- This form is slowly converted to the GDP-bound form by the intrinsic GTPase activity of Ras
- This activity is greatly enhanced byGTPase-activating proteins (GAPs) which subsequently lead to removal of the GTP molecule and replacement with GDP
- Maintenance of Ras in the GTP form can lead to transformation
- One class of Ras mutations, commonly found in human tumors, results in an accumulation of Ras-GTP
- The mutant Ras can bind GAP, but GAP bound in this manner seems unable to affect the Ras-GTPase activity.
Compare Similar Items
Show Difference
Antigen: Ras
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Ras (Ha-ras) aa. 1-190
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1 κ
Applications: Western Blot
Clone: 18
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Ras
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Ras (Ha-ras) aa. 1-190
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
18
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Phosphotyrosine
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA and glycerol.
Immunogen: __
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG2b
Applications: Western Blot
Clone: PY20
Conjugate: HRP
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Phosphotyrosine
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA and glycerol.
Immunogen:
__
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG2b
Applications:
Western Blot
Clone:
PY20
Conjugate:
HRP
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Phosphotyrosine
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA and glycerol.
Immunogen: __
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG2b
Applications: Western Blot
Clone: PY20
Conjugate: HRP
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Phosphotyrosine
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA and glycerol.
Immunogen:
__
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG2b
Applications:
Western Blot
Clone:
PY20
Conjugate:
HRP
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: EGF Receptor
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human EGF Receptor aa. 1020 to 1046
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1
Applications: Western Blot
Clone: 13
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
EGF Receptor
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human EGF Receptor aa. 1020 to 1046
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1
Applications:
Western Blot
Clone:
13
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.