BDB610139
PTP1B Mouse, Unlabeled, Clone: 15, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610139-Each-of-1 | In Stock | ₹ 22,245.60 |
BDB610139 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,245.60
GST (18%): ₹ 4,004.208
Total Price: ₹ 26,249.808
Antigen
PTP1B
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype
IgG2a
Applications
Western Blot
Clone
15
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Description
- PTP1B is a member of the class of enzymes termed protein tyrosine phosphatases(PTPs)
- This 50 kDa protein contains a conserved phosphatases domain at residues 30-278 and is localized to the cytoplasmic face of the endoplasmic reticulum by its C-terminal 35 residues
- Its interactions with other proteins are mediated by proline-rich regions and SH2 compatible sequences
- PTP1B is thought to act as a negative regulator in insulin signaling
- Insulin stimulation induces its association with the insulin receptor and tyrosine phosphorylation
- Its overexpression inhibits proximal and distal insulin signaling events, possibly due to receptor dephosphorylation
- Microinjection of PTP1B into Xenopus oocytes blocks insulin-induced maturation
- Additional studies demonstrate that PTP1B undergoes cell cycle-dependent and/or stress-induced serine phosphorylation
- This suggests further regulatory roles that are not yet defined.
Compare Similar Items
Show Difference
Antigen: PTP1B
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG2a
Applications: Western Blot
Clone: 15
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
PTP1B
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG2a
Applications:
Western Blot
Clone:
15
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Eps8
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 15
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Eps8
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
15
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Eps8
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 15
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Eps8
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
15
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: c-Raf
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 53
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
c-Raf
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
53
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.