BDB610291
DAP Kinase Mouse anti-Human, Unlabeled, Clone: 17, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610291-Each-of-1 | In Stock | ₹ 45,004.56 |
BDB610291 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,004.56
GST (18%): ₹ 8,100.821
Total Price: ₹ 53,105.381
Antigen
DAP Kinase
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity
150 μg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1
Applications
Western Blot
Clone
17
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Description
- Chronic exposure to extracellular signals such as interferons induce the inhibition of cell proliferation followed by cell death
- The gene for DAP Kinase (Death Associated Protein Kinase) was identified using a novel approach named Technical Knockout
- Briefly, Hela cells were transfected with an antisense cDNA expression library, then exposed to Interferon-γ
- The surviving cells, with their antisense cDNAs, were rescued and the “protecting” genes isolated
- The DAP Kinase gene encodes a protein of 1423 amino acids, a molecular weight of 160kDa, a kinase domain at its amino terminal region, ankyrin repeats in the middle region, and a death domain at the extreme C-terminus
- DAP Kinase phosphorylates at Ser/Thr residues in a Ca 2 + /Calmodulin-dependent fashion
- It has been demonstrated that Ca 2 + /Calmodulin binds directly to DAP Kinase at its amino terminal region
- In addition, immunostaining studies localized DAP Kinase in association with the actin filaments where it may phosphorylate myosin light chain
- Thus, this novel cytoskeletal and Ca 2 + /Calmodulin-dependent protein kinase plays a role in interferon-γ-induced cell death
- Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Compare Similar Items
Show Difference
Antigen: DAP Kinase
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: 17
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
DAP Kinase
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
17
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: eNOS/NOS Type III
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Applications: Western Blot
Clone: 3
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
eNOS/NOS Type III
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
3
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: eNOS/NOS Type III
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Applications: Western Blot
Clone: 3
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
eNOS/NOS Type III
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
3
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: nNOS
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG2a
Applications: Western Blot
Clone: 16
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
nNOS
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG2a
Applications:
Western Blot
Clone:
16
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.