BDB611116
Btk Mouse anti-Human, Unlabeled, Clone: 53/BTK, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB611116-Each-of-1 | In Stock | ₹ 24,598.50 |
BDB611116 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,598.50
GST (18%): ₹ 4,427.73
Total Price: ₹ 29,026.23
Antigen
Btk
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human N-Terminal Btk aa. 2-172 Recombinant Protein
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG2a
Applications
Western Blot
Clone
53/BTK
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Bruton's tyrosine kinase (Btk) is a nonreceptor tyrosine kinase whose function is critical for proper B cell development and signaling
- It is a member of the Tec family of kinases which includes Tec and Itk
- In addition to an N-terminal pleckstrin homology (PH) domain, the Tec proteins contain Src homology domains 2 and 3 (SH2 and SH3) and a stretch of 60-80 amino acids between the PH and SH3 domains termed the Tec homology domain
- The activity of Btk is regulated by Src-mediated phosphorylation of the kinase domain at tyrosine 551
- This event induces Btk kinase activity and subsequent autophosphorylation at tyrosine 223 in the SH3 domain
- Phosphorylated Btk then associates with the cell membrane via the interaction of the PH domain with phosphatidylinositol 3, 4, 5-triphosphate
- The PH domain is essential for proper activation and function of Btk
- A mutation in the PH domain results in Xid, murine X-linked immunodeficiency, and human X-linked agammaglobulinemia
- Host Species: Mouse Clone: 53 Isotype: IgG2a Species Reactivity: Human Immunogen: Human N-Terminal Btk aa
- 2-172 Recombinant Protein Formula Weight [Chemical]: 77kDa Immunofluorescence, Western Blotting
Compare Similar Items
Show Difference
Antigen: Btk
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human N-Terminal Btk aa. 2-172 Recombinant Protein
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Applications: Western Blot
Clone: 53/BTK
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Btk
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human N-Terminal Btk aa. 2-172 Recombinant Protein
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Applications:
Western Blot
Clone:
53/BTK
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Btk
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human N-Terminal Btk aa. 2-172 Recombinant Protein
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Applications: Western Blot
Clone: 53/BTK
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Btk
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human N-Terminal Btk aa. 2-172 Recombinant Protein
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Applications:
Western Blot
Clone:
53/BTK
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: SRPK2
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human SRPK2 aa. 363-485
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 23
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
SRPK2
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human SRPK2 aa. 363-485
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
23
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: G3BP
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human G3BP aa. 210-323
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: 23
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
G3BP
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human G3BP aa. 210-323
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
23
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.