BDB740228

CD11a Rat anti-Mouse, BUV395, Clone: M17/4, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740228-Each-of-1 In Stock ₹ 34,052.88

BDB740228 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

CD11a

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Itgal; Integrin alpha-L; Integrin αL; ITAL; LFA-1A; LFA-1α; Ly-15

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

M17/4

Conjugate

Brilliant Ultraviolet 395

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

C57BL/6 Mouse Splenic Secondary Cytotoxic T Lymphocytes

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The M17/4 antibody reacts with the 180 kDa α L chain of LFA-1 (CD11a/CD18, α L β 2 integrin), a heterodimeric surface glycoprotein expressed on almost all leukocytes
  • CD8a+CD8b- intestinal intraepithelial T lymphocytes, which are believed to be thymus independent, do not express CD11a
  • LFA-1 mediates a variety of heterotypic and homotypic intercellular adhesions through interaction with ICAM-1 (CD54) and ICAM-2 (CD102), including participation in the immunological synapses between CD8+ T lymphocytes and antigen-presenting cells
  • mAb M17/4 blocks a variety of LFA-1-mediated cells interactions in vitro, and costimulatory effects have also been described
  • In vivo treatment with M17/4 mAb reduces the severity of graft-versus-host reactions, prolongs allograft survival, inhibits the development of autoimmunity, and blocks substance P-induced leukocyte migration
  • The M17/4 and 2D7 (Cat
  • No
  • 553120) antibodies are reported to recognize different epitopes of the CD11a molecule.

Compare Similar Items

Show Difference

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BD Biosciences

BDB740228

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Antigen:
CD11a

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Itgal; Integrin alpha-L; Integrin αL; ITAL; LFA-1A; LFA-1α; Ly-15

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
M17/4

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
C57BL/6 Mouse Splenic Secondary Cytotoxic T Lymphocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740229

--


Antigen:
CD61

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Itgb3; Integrin beta-3; INGRB3; Platelet glycoprotein IIIa; GP3A; GPIIIa

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
2C9.G2

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse T-cell Hybridoma 2B4 Vitronectin Receptor

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740230

--


Antigen:
CD122

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Il2rb; Il-2Rbeta; IL-2Rβ; IL-15Rbeta; IL-2/15 Receptor-beta; IL-2/15Rbeta

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
TM-Beta 1

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse IL-2Rβ Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740231

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Antigen:
CD31

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
EndoCAM; GPIIA; PECA1; PECAM1; Platelet endothelial cell adhesion molecule

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
MEC 13.3

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
129/Sv mouse-derived endothelioma cell line tEnd.1

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.