BDB740557

Siglec-F Rat anti-Mouse, Brilliant Violet 650, Clone: E50-2440, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740557-Each-of-1 In Stock ₹ 34,224.00

BDB740557 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

Siglec-F

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Siglecf; Siglec5; sialic acid binding Ig-like lectin 5; SIGL5; Siglec-5

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

E50-2440

Conjugate

Brilliant Violet 650

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse Siglec-F and human IgG Fc recombinant fusion protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The E50-2440 monoclonal antibody specifically recognizes Siglec-F
  • Siglecs are the s ialic acid-binding immunoglobulin superfamily lectins defined in the human, each of which has a distinctive expression pattern in the hematopoietic system and at least some of which are known to mediate cell-cell interactions
  • Orthologous proteins of human Siglec-1 (Sialoadhesin or CD169), Siglec-2 (CD22), and Siglec-4 (myelin-associated glycoprotein) have been characterized in the mouse
  • Human Siglec-3 (CD33) and Siglecs-5 through -10 are encoded by a cluster of closely related genes, and each has two cytoplasmic ITIM (Immunoreceptor Tyrosine-based Inhibitory Motifs)
  • Similarly, mouse Siglec-F is encoded by a gene in a syntenic cluster in the mouse, and the protein has sialic acid-binding activity and an intracytoplasmic ITIM
  • Its expression pattern differs from those of the human Siglec-3-related proteins in that it is found on immature cells of the myelomonocytic lineage, with reduced expression on mature neutrophils and monocytes, and not on lymphoid cells
  • It has been proposed that mAb E50-2440 may be used for identification of immature myelomonocytic cells in the mouse.

Compare Similar Items

Show Difference

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BD Biosciences

BDB740557

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Antigen:
Siglec-F

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Siglecf; Siglec5; sialic acid binding Ig-like lectin 5; SIGL5; Siglec-5

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
E50-2440

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse Siglec-F and human IgG Fc recombinant fusion protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740558

--


Antigen:
CD180

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly78; Ly-78; Lymphocyte antigen 78; RP105; Radioprotective 105 kDa protein

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
RP/14

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
BALB/c mouse splenocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740559

--


Antigen:
CD326

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ep-CAM; EGP; EGP-2; Egp314; GA733-2; TROP1; Tacsd1; Tacstd1; Ly74; gp40

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
G8.8

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Glycoconjugates from BALB/c mouse-derived TE-71 medullary thymic epithelial cell line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740560

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Antigen:
CD223

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Lag3; LAG-3; Lymphocyte-activation gene 3; Ly66

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
C9B7W

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse LAG3 fusion protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.