BDB740842

CD5 Rat anti-Mouse, Brilliant Violet 786, Clone: 53-7.3, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740842-Each-of-1 In Stock ₹ 34,224.00

BDB740842 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD5

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Lymphocyte antigen 1; Cd5; Ly-12; Ly-A; Lyt-1

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

53-7.3

Conjugate

Brilliant Violet 786

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse Thymus / Spleen

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 53-7.3 monoclonal antibody specifically binds to a monomorphic epitope of CD5, a member of the scavenger receptor cysteine-rich protein superfamily and the major ligand of CD72, found on thymocytes, T lymphocytes, thymic NKT cells, and a subset of B lymphocytes, but not on NK cells or splenic NKT cells
  • The level of surface CD5 expression is developmentally regulated in the thymus, starting with low levels on CD4-CD8- thymocytes and increasing as they mature to CD4+CD8+ then CD4+CD8- or CD4-CD8+ thymocytes
  • Relatively high levels are maintained on peripheral T lymphocytes
  • The level of CD5 antigen detected on T helper cells has been reported to be somewhat higher than that on T cytotoxic/suppressor and B cells
  • Few, if any, intestinal intraepithelial lymphocytes bearing the γδ T-cell receptor express CD5
  • Phenotypic, anatomical, functional, developmental, and pathogenic characteristics of peripheral CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells
  • The frequency of these CD5+ B cells has been reported to show strain-dependent variation
  • An additional population of CD5+ B lymphocytes resides in the thymus, where it matures from intrathymic B-cell progenitors
  • It has been proposed that CD5 is a costimulatory molecule which mediates interactions of cells in the immune system and negatively regulates signal transduction mediated by the T-cell receptor and B-cell receptor
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

Compare Similar Items

Show Difference

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BD Biosciences

BDB740842

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Antigen:
CD5

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Lymphocyte antigen 1; Cd5; Ly-12; Ly-A; Lyt-1

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
53-7.3

Conjugate:
Brilliant Violet 786

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse Thymus / Spleen

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740843

--


Antigen:
CD8b.2

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly-3.2; Lyt-3.2; CD8b.2

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
53-5.8

Conjugate:
Brilliant Violet 786

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse thymus or spleen

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB740848

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Antigen:
CD229.1

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly-9.1; T100; CD229; Lgp100; SLAMF3

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
30C7

Conjugate:
Brilliant Violet 786

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
SJL/J mouse splenocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB740850

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Antigen:
Ly-6G and Ly-6C

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
RB6-8C5

Conjugate:
Brilliant Violet 786

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Not Reported

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.