BDB740874
CD154 Hamster anti-Mouse, Brilliant Violet 786, Clone: MR1, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740874-Each-of-1 | In Stock | ₹ 34,224.00 |
BDB740874 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
CD154
Classification
Monoclonal
Concentration
0.2mg/mL
Description
CD40 Ligand; CD40L; gp39; Ly-62; Tnfsf5; T-BAM; HIGM1; IMD3
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG3 κ
Applications
Flow Cytometry
Clone
MR1
Conjugate
Brilliant Violet 786
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Activated mouse Th1 clone D1.6
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The MR1 monoclonal antibody specifically binds to CD154 (CD40 Ligand, gp39), an accessory molecule expressed on activated T helper (CD4+) lymphocytes
- CD154 has also been detected on other types of leukocytes, including CD8+ T cells, medullary thymocytes, activated CD4+ NK-T cells, and human NK cells
- CD154 plays an important role in costimulatory interactions between T and B lymphocytes and between antigen-presenting cells and lymphocytes, regulating the immune response at multiple levels
- MR1 mAb inhibits in vitro activation of B lymphocytes by T helper cells by blocking interaction of gp39 with CD40
- In vitro interactions of T cells and antigen-presenting cells can also be blocked by the MR1 antibody
- In vivo treatment with MR1 antibody blocks the development of experimental autoimmune disease, inhibits formation of germinal centers and generation of memory B cells, reduces T-lymphocyte responses to allogeneic cells and allografts, prevents intrathymic deletion of self-reactive T lymphocytes, and disrupts antigen-specific T-cell responses.
Compare Similar Items
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Antigen: CD154
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: CD40 Ligand; CD40L; gp39; Ly-62; Tnfsf5; T-BAM; HIGM1; IMD3
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG3 κ
Applications: Flow Cytometry
Clone: MR1
Conjugate: Brilliant Violet 786
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Activated mouse Th1 clone D1.6
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD154
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
CD40 Ligand; CD40L; gp39; Ly-62; Tnfsf5; T-BAM; HIGM1; IMD3
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG3 κ
Applications:
Flow Cytometry
Clone:
MR1
Conjugate:
Brilliant Violet 786
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Activated mouse Th1 clone D1.6
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: TER-119/Erythroid Cells
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Lymphocyte antigen 76; Ly76; Ly-76; TER-119; Ter119
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: TER-119
Conjugate: Brilliant Violet 786
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse Fetal Liver
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
TER-119/Erythroid Cells
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Lymphocyte antigen 76; Ly76; Ly-76; TER-119; Ter119
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
TER-119
Conjugate:
Brilliant Violet 786
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse Fetal Liver
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD86
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: B7-2; Ly-58; Cd28l2; Early T-cell costimulatory molecule 1; ETC1; MB7; CLS1
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: GL1
Conjugate: Brilliant Violet 786
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse (CBA/Ca) LPS-activated splenic B Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD86
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
B7-2; Ly-58; Cd28l2; Early T-cell costimulatory molecule 1; ETC1; MB7; CLS1
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
GL1
Conjugate:
Brilliant Violet 786
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse (CBA/Ca) LPS-activated splenic B Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD31
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Platelet endothelial cell adhesion molecule; Pecam1; PECAM-1; Pecam-1
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 390
Conjugate: Brilliant Violet 786
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: C3H/HeJ mouse hematopoietic progenitor cell line 32D
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD31
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Platelet endothelial cell adhesion molecule; Pecam1; PECAM-1; Pecam-1
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
390
Conjugate:
Brilliant Violet 786
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
C3H/HeJ mouse hematopoietic progenitor cell line 32D
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.