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BDB742382

Vβ 8 T-Cell Receptor Mouse anti-Mouse, BUV395, Clone: F23.1, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB742382-Each-of-1 In Stock ₹ 35,600.00

BDB742382 - Each of 1

₹ 35,600.00

In Stock

Quantity

1

Base Price: ₹ 35,600.00

GST (18%): ₹ 6,408.00

Total Price: ₹ 42,008.00

Antigen

Vβ 8 T-Cell Receptor

Clone

F23.1

Conjugate

Brilliant Ultraviolet 395

Gene Alias

TCR V beta 8, TCR V beta 8.1/8.2/8.3

Immunogen

BALB.B Mouse Lymph-Node and Spleen T Cells

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Description

  • The F23.1 antibody specifically reacts with the V β 8.1, V β 8.2, and V β 8.3 T-cell receptors (TCR) of mice having the b haplotype ( e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C58, DBA/1, DBA/2) of the Tcrb gene complex
  • The Tcrb-V8 subfamily gene loci are deleted in mice having the a ( e.g., C57BR, C57L, SJL, SWR) or c ( e.g., RIII) haplotype
  • V β 8.1 TCR-bearing T lymphocytes are clonally eliminated in mice expressing superantigen coded by Mtv-7 (Mls-1a, Mlsa) provirus ( e.g., AKR, CBA/J, C58, DBA/2), and activation or elimination of V β 8.1 TCR-expressing T cells by this determinant is partially dependent upon presentation by I-E
  • Mtv-43 and/or exogenous MMTV-SW superantigens also cause incomplete elimination of V β 8.1 TCR-bearing T cells
  • In addition to expression on conventional T lymphocytes, V β 8.2 is the predominant β chain of the TCR on NK-T cells
  • Staphylococcal enterotoxin B, in association with antigen-presenting cells expressing I-A and/or I-E, stimulates lymphocytes bearing V β 8 TCR and selectively eliminates those T cells in vivo
  • Soluble and plate-bound F23.1 antibody activates V β 8 TCR-bearing T cells, soluble antibody blocks cytolysis mediated by V β 8 TCR-bearing cytotoxic T lymphocytes, and in vivo treatment of neonatal mice can arrest intrathymic maturation of V β 8 TCR-bearing T cells
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
  • BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
  • With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
  • This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

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Show Difference

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BD Biosciences

BDB742382

--

Antigen:
Vβ 8 T-Cell Receptor
Clone:
F23.1
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
TCR V beta 8, TCR V beta 8.1/8.2/8.3
Immunogen:
BALB.B Mouse Lymph-Node and Spleen T Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ

Img

BD Biosciences

BDB742384

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Antigen:
IgD[b]
Clone:
217-170
Conjugate:
Brilliant Violet 510
Gene Alias:
Igh-5b, Ighd, immunoglobulin heavy constant delta
Immunogen:
Not reported
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ

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BD Biosciences

BDB742385

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Antigen:
IgD[b]
Clone:
217-170
Conjugate:
Brilliant Violet 605
Gene Alias:
Igh-5b, Ighd, immunoglobulin heavy constant delta
Immunogen:
Not reported
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ

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BD Biosciences

BDB742386

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Antigen:
IgD[b]
Clone:
217-170
Conjugate:
Brilliant Violet 650
Gene Alias:
Igh-5b, Ighd, immunoglobulin heavy constant delta
Immunogen:
Not reported
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ