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BDB742393

CD8b Mouse anti-Human, Brilliant Violet 650, Clone: 2ST8.5H7, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB742393-Each-of-1 In Stock ₹ 47,614.14

BDB742393 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD8b

Clone

2ST8.5H7

Conjugate

Brilliant Violet 650

Gene Alias

CD8B, CD8B1, CD8 beta, CD8β, Leu2, Ly3, LYT3

Immunogen

CD8+ suppressor T-cell

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Description

  • The 2ST8.5H7 monoclonal antibody specifically recognizes an epitope formed by the combination of CD8 alpha and beta chains
  • The majority of peripheral blood CD8+ T lymphocytes expresses a CD8 cells and CD8+ CD8 s
  • The 2ST8.5H7 antibody can therefore be used to selectively bind to CD8+ T cells while excluding CD8+ NK cells
  • CD8 binds to class I major histocompatibility (MHC) molecules, resulting in increased adhesion between the CD8+ T lymphocytes and target cells
  • Binding of CD8 to class I MHC molecules enhances the activation of resting T lymphocytes
  • CD8 is coupled to a protein tyrosine kinase, p56lck
  • The CD8:p56lck complex can play a role in T-lymphocyte activation through mediation of the interactions between CD8 and the CD3/TCR complex
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

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BD Biosciences

BDB742393

--

Antigen:
CD8b
Clone:
2ST8.5H7
Conjugate:
Brilliant Violet 650
Gene Alias:
CD8B, CD8B1, CD8 beta, CD8β, Leu2, Ly3, LYT3
Immunogen:
CD8+ suppressor T-cell
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ

Img

BD Biosciences

BDB742397

--

Antigen:
CD37
Clone:
M-B371
Conjugate:
Brilliant Violet 421
Gene Alias:
GP52-40, Tetraspanin-26, TSPAN26, Tspan-26
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

BDB742399

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Antigen:
CD37
Clone:
M-B371
Conjugate:
Brilliant Violet 605
Gene Alias:
GP52-40, Tetraspanin-26, TSPAN26, Tspan-26
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

BDB742403

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Antigen:
CD37
Clone:
M-B371
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
GP52-40; Tetraspanin-26; TSPAN26; Tspan-26
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BUV395 under optimal conditions that minimize unconjugated dye and antibody.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ