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BDB742523

CD39 Mouse anti-Human, Brilliant Violet 786, Clone: TU66 (also known as Tü 66, Tü66), BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742523-Each-of-1 In Stock ₹ 49,528.50

BDB742523 - Each of 1

₹ 49,528.50

In Stock

Quantity

1

Base Price: ₹ 49,528.50

GST (18%): ₹ 8,915.13

Total Price: ₹ 58,443.63

Antigen

CD39

Clone

TU66 (also known as Tü 66, Tü66)

Conjugate

Brilliant Violet 786

Gene Alias

ENTPD1, NTPDase-1, Ecto-ATPase 1, Ecto-ATPDase 1

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The TU66 monoclonal antibody reacts with human CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), an ectoenzyme that degrades ATP to AMP
  • It is a member of the ectonucleoside triphosphate dihydrolases (E-NTPDases) family involved in the regulation of extracellular nucleotide catabolism by controlling the extracellular nucleoside triphosphate pool (NTP)
  • CD39 is expressed on a subset of T cells, B cells and dendritic cells, with weak staining of monocytes and granulocytes
  • Recently, CD39 has been found to be expressed primarily by immune-suppressive Foxp3(+) regulatory T (Treg) cells in both human and mice
  • In humans, CD39 is restricted to a subset of Foxp3+ regulatory effector/memory-like T cells
  • In mice, the enzyme is present on most, if not all, CD4+CD25+ cells
  • CD39 expression is driven by Foxp3 and it is thought that CD39 allows Treg cells to enter inflamed areas where high levels of ATP are present
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
  • BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
  • BV786 offers a bright choice for the 6th detector off the violet laser.

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BD Biosciences

BDB742523

--

Antigen:
CD39
Clone:
TU66 (also known as Tü 66, Tü66)
Conjugate:
Brilliant Violet 786
Gene Alias:
ENTPD1, NTPDase-1, Ecto-ATPase 1, Ecto-ATPDase 1
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB742525

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Antigen:
CD28
Clone:
L293
Conjugate:
Brilliant Violet 421
Gene Alias:
CD28 antigen, T44, Tp44, TP44, Leu28
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD28
Clone:
L293
Conjugate:
Brilliant Violet 650
Gene Alias:
CD28 antigen, T44, Tp44, TP44, Leu28
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

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Antigen:
CD28
Clone:
L293
Conjugate:
Brilliant Violet 711
Gene Alias:
CD28 antigen, T44, Tp44, TP44, Leu28
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.