BDB742611

HLA-DQ Mouse anti-Human, Brilliant Violet 650, Clone: Tu169, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742611-Each-of-1 In Stock ₹ 47,400.24

BDB742611 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

HLA-DQ

Clone

Tu169

Conjugate

Brilliant Violet 650

Gene Alias

MHC class II HLA-DQ, MHC HLA-DQ

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The TU169 monoclonal antibody specifically binds to the human Major Histocompatibility Complex (MHC) Class II HLA-DQ1 and DQ2 antigens and weakly to HLA-DQ3
  • HLA-DQ antigens exits as heterodimers comprised of polymorphic transmembrane HLA-DQ alpha and beta glycoproteins
  • HLA-DQ is expressed primarily on B cells, monocytes, macrophages, dendritic cells and activated T lymphocytes
  • HLA-DQ is involved in presenting peptidic antigens to CD4+ T lymphocytes
  • This antibody does not cross-react with HLA-DR2 and HLA-DR7
  • This antibody fixes complement
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

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BDB742611

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Antigen:
HLA-DQ

Clone:
Tu169

Conjugate:
Brilliant Violet 650

Gene Alias:
MHC class II HLA-DQ, MHC HLA-DQ

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD59

Clone:
TH9

Conjugate:
Brilliant Violet 605

Gene Alias:
MACIF, Membrane attack complex inhibition factor, Protectin

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD59

Clone:
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Conjugate:
Brilliant Violet 650

Gene Alias:
MACIF, Membrane attack complex inhibition factor, Protectin

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD59

Clone:
TH9

Conjugate:
Brilliant Violet 786

Gene Alias:
MACIF, Membrane attack complex inhibition factor, Protectin

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.