BDB742762
CD21 Mouse anti-Human, Brilliant Violet 650, Clone: 1048, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742762-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB742762 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD21
Clone
1048
Conjugate
Brilliant Violet 650
Gene Alias
CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen
Human CR2 Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- CD21 is a 145 kDa transmembrane glycoprotein that is expressed on mature B cells, follicular dendritic cells, a subset of immature thymocytes and on some epithelial cells
- CD21 is also known as the C3d Receptor, Complement Receptor 2 (CR2), and the Epstein-Barr Virus receptor, (EBV-R)
- CD21 is part of a large signal-transduction complex that also includes CD19, CD81 and Leu13
- CR2 serves as a receptor for the activation fragments of complement component C3, i.e
- C3d, iC3d, and C3dg and C3d-bound antigens and plays a central role in the immune response by amplifying B-cell activation and proliferation
- CR2 is also the receptor for EBV by binding its surface glycoprotein gp350/220
- Anti-human CR2 hybridomas were generated from Cr2-/-mice (lacking the cr2 gene, that encodes CR2 and CR1 in mice) immunized with the recombinant protein representing the first two amino-terminal short consensus repeats (SRC) of human CR2, SCR1-2
- Both the C3d and EBV binding sites of hu CR2 were localized to these sites
- Clone 1048 has been reported to specifically react with CR2-expressing cells and to inhibit CR2 interactions with C3 fragments or the EBV surface protein, gp350/220
- The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
Compare Similar Items
Show Difference
Antigen: CD21
Clone: 1048
Conjugate: Brilliant Violet 650
Gene Alias: CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen: Human CR2 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD21
Clone:
1048
Conjugate:
Brilliant Violet 650
Gene Alias:
CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen:
Human CR2 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD21
Clone: 1048
Conjugate: Brilliant Violet 711
Gene Alias: CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen: Human CR2 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD21
Clone:
1048
Conjugate:
Brilliant Violet 711
Gene Alias:
CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen:
Human CR2 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD21
Clone: 1048
Conjugate: Brilliant Violet 786
Gene Alias: CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen: Human CR2 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD21
Clone:
1048
Conjugate:
Brilliant Violet 786
Gene Alias:
CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen:
Human CR2 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD21
Clone: 1048
Conjugate: Brilliant Ultraviolet 395
Gene Alias: CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen: Human CR2 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD21
Clone:
1048
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
CR2, Complement receptor type 2, C3DR, EBV-R, Epstein-Barr virus receptor
Immunogen:
Human CR2 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ