BDB742767

CD282 (TLR2) Mouse anti-Human, Brilliant Violet 510, Clone: 11G7, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742767-Each-of-1 In Stock ₹ 47,614.14

BDB742767 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD282 (TLR2)

Clone

11G7

Conjugate

Brilliant Violet 510

Gene Alias

TLR2, CD282, TIL4, Toll/interleukin-1 receptor-like protein 4

Immunogen

Human TLR2-transfected cell line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The 11G7 monoclonal antibody specifically binds to human CD282, which is also known as Toll-like receptor 2 (TLR2)
  • CD282 is expressed on monocytes, granulocytes, and dendritic cells
  • Toll-like receptors (TLRs) play a critical role in antimicrobial resistance
  • Moreover, TLRs have been shown to activate a number of signal transduction pathways which lead to the induction of genes involved in host defense
  • TLRs are type-1 transmembrane receptors characterized by the presence of extracellular leucine-rich repeat and intracellular Toll/IL-1 receptor domains
  • At least 12 mammalian TLRs have been identified, each recognizing a distinct bacterial or viral pathogen-associated molecular pattern, termed PAMP
  • Peptidoglycan from Gram-positive bacteria, lipoproteins and lipopeptides from several bacteria, glycophosphatidylinositol, lipoarabinomannan, porins, and zymosan from yeast have been reported to be the ligands for TLR2
  • It has been reported that mAb 11G7 inhibits the production of inflammatory cytokines via certain TLR2 ligands including TLR2/TLR1 ligands, lipoarabinomannan and PAM3CSK4
  • However, 11G7 antibody does not inhibit the production of inflammatory cytokines with zymosan, a TLR2/TLR6 ligand
  • Please note that this application has not been tested at BD Biosciences Pharmingen
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
  • BV510 is a polymer-based dye that is brighter than BD Horizon V500
  • Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.

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BD Biosciences

BDB742767

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Antigen:
CD282 (TLR2)

Clone:
11G7

Conjugate:
Brilliant Violet 510

Gene Alias:
TLR2, CD282, TIL4, Toll/interleukin-1 receptor-like protein 4

Immunogen:
Human TLR2-transfected cell line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB742768

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Antigen:
CD282 (TLR2)

Clone:
11G7

Conjugate:
Brilliant Violet 605

Gene Alias:
TLR2, CD282, TIL4, Toll/interleukin-1 receptor-like protein 4

Immunogen:
Human TLR2-transfected cell line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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Antigen:
CD282 (TLR2)

Clone:
11G7

Conjugate:
Brilliant Violet 711

Gene Alias:
TLR2, CD282, TIL4, Toll/interleukin-1 receptor-like protein 4

Immunogen:
Human TLR2-transfected cell line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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BD Biosciences

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Antigen:
CD282 (TLR2)

Clone:
11G7

Conjugate:
Brilliant Ultraviolet 395

Gene Alias:
TLR2, CD282, TIL4, Toll/interleukin-1 receptor-like protein 4

Immunogen:
Human TLR2-transfected cell line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ