BDB742848

P-glycoprotein Mouse anti-Human, Brilliant Violet 510, Clone: 17F9, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB742848-Each-of-1 In Stock ₹ 47,400.24

BDB742848 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

P-glycoprotein

Clone

17F9

Conjugate

Brilliant Violet 510

Gene Alias

CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1

Immunogen

Human MDR1 Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Description

  • The 17F9 monoclonal antibody specifically binds to the 170-180 kDa transmembrane glycoprotein (P-glycoprotein), a product of the multidrug resistance-1 (MDR1) gene
  • This glycoprotein is expressed on MDR positive cells and has been reported to be expressed on many normal tissues, such as adrenal glands and endothelium, in the brain and skin
  • P-glycoprotein is known to impart drug resistance to cells by pumping many anti-cancer drugs out of the cytoplasm
  • 17F9 antibody is able to partially block the binding of UIC2 antibody (another MDR-specific monoclonal antibody)
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
  • BV510 is a polymer-based dye that is brighter than BD Horizon V500
  • Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.

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BD Biosciences

BDB742848

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Antigen:
P-glycoprotein

Clone:
17F9

Conjugate:
Brilliant Violet 510

Gene Alias:
CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1

Immunogen:
Human MDR1 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Img

BD Biosciences

BDB742849

--


Antigen:
P-glycoprotein

Clone:
17F9

Conjugate:
Brilliant Violet 605

Gene Alias:
CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1

Immunogen:
Human MDR1 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Img

BD Biosciences

BDB742850

--


Antigen:
P-glycoprotein

Clone:
17F9

Conjugate:
Brilliant Violet 650

Gene Alias:
CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1

Immunogen:
Human MDR1 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Img

BD Biosciences

BDB742852

--


Antigen:
P-glycoprotein

Clone:
17F9

Conjugate:
Brilliant Violet 786

Gene Alias:
CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1

Immunogen:
Human MDR1 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ